Occurrence and Fate of Amoxicillin and Penicillin G Antibiotics in Hospital Wastewater Treatment Plants: A Case Study - Gonbad Kavous, Iran

IF 0.8 4区 化学 Q4 CHEMISTRY, MULTIDISCIPLINARY
M. Golchin, Mohammad-Yaser Khani, M. Sadani, M. Sadeghi, Mahsa Jahangiri-rad
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引用次数: 1

Abstract

ABSTRACT Release of antibiotics to the environment as a result of wastewater effluent discharge is a cause for concern worldwide, as they pose a potential threat to human health and the earth ecosystem. Penicillin and amoxicillin are widely used antibiotics. Despite their rapid hydrolysis in aqueous matrices, their presence in the environment is widely investigated. The current study reported and analysed the current state of four hospital wastewater treatment plants (WWTPs) in Gonbad Kavous, Iran, during 2019, from the perspective of amoxicillin and penicillin G removals. WWTPs were sampled at various stages of the treatment process to determine at which stage the antibiotics are being removed. Concentrations of amoxicillin and penicillin G in raw wastewater, analysed by HPLC, varied from 0.35 to 1.02 and 0.02-0.31 /AgL-1, respectively. These values reduced in the final effluent, corresponding to overall efficiency in removing the studied antibiotics of 20-60.5%. Anaerobic processes (i.e. septic tank) slightly outperformed aerobic biological processes for both antibiotics' removal, and penicillin G was removed more efficiently than amoxicillin. Effects of wastewater physicochemical properties, including chemical oxygen demand (COD), biochemical oxygen demand (BOD), and total suspended solids (TSS) on antibiotics removal, were also studied. Whereas statistically significant correlations were noticed between COD, amoxicillin and penicillin G removals, their decline showed no correlation with TSS removal. Our study shows that despite the deployment of treatment plants, a considerable amount of antibiotics is released into receiving water bodies, resulting in significant amounts of these pharmaceuticals entering the environment. There is abundant room for further progress in the detection and quantification of pharmaceuticals and other emerging contaminants in hospital wastewaters and their metabolites and biodegradation products. Keywords: amoxicillin; penicillin G; high-performance liquid chromatography; hospital wastewater treatment plants; removal.
阿莫西林和青霉素G抗生素在医院污水处理厂的发生和命运:一个案例研究-伊朗Gonbad Kavous
由于废水排放导致抗生素释放到环境中,对人类健康和地球生态系统构成潜在威胁,因此引起了全世界的关注。青霉素和阿莫西林是广泛使用的抗生素。尽管它们在水基质中快速水解,但它们在环境中的存在被广泛研究。本研究从阿莫西林和青霉素G去除的角度报告并分析了2019年伊朗Gonbad Kavous四家医院废水处理厂(WWTPs)的现状。在处理过程的不同阶段对污水处理剂进行取样,以确定在哪个阶段去除抗生素。高效液相色谱法测定原废水中阿莫西林和青霉素G的浓度分别为0.35 ~ 1.02和0.02 ~ 0.31 /AgL-1。这些值在最终流出物中降低,相当于去除所研究抗生素的总效率为20-60.5%。厌氧工艺(即化粪池)在抗生素去除方面略优于好氧生物工艺,青霉素G的去除效率高于阿莫西林。研究了废水理化性质,包括化学需氧量(COD)、生化需氧量(BOD)和总悬浮固体(TSS)对抗生素去除的影响。虽然COD、阿莫西林和青霉素G去除率之间存在统计学上的显著相关性,但它们的下降与TSS去除率没有相关性。我们的研究表明,尽管部署了处理厂,但仍有相当数量的抗生素被释放到接收水体中,导致大量这些药物进入环境。在医院废水及其代谢物和生物降解产物中药物和其他新出现的污染物的检测和定量方面,还有很大的进一步进展空间。关键词:阿莫西林;青霉素G;高效液相色谱法;医院污水处理厂;去除。
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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
6
审稿时长
>12 weeks
期刊介绍: Original work in all branches of chemistry is published in the South African Journal of Chemistry. Contributions in English may take the form of papers, short communications, or critical reviews.
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