Pilot Study to Determine the Prevalence of CYP2B6*6(C.516G>T), CYP2C19*2 (C.681G>A) and CYP2C19*3 (C.636G>A) in Breast Cancer Patients versus Normal Healthy Controls among Three Major Ethnic Groups in Singapore

Abstract

Background: Breast cancer is the top cancer suffered by women worldwide and is the leading cause of cancer mortality for women living in Singapore. Unfortunately, most of breast cancer cases are detected at a later stage of disease development and cripple the outcome of the therapy. This is a study to identify potential breast cancer susceptibility gene polymorphisms.