Effect of Plasma Discharge on Epidermal Layer Structure in Pig Skin

Q3 Physics and Astronomy

Plasma Medicine Pub Date : 2021-01-01 DOI:10.1615/plasmamed.2021036925

A. Yahaya, J. Krištof, M. Blajan, Fariha Mustafa, K. Shimizu

引用次数: 0

Abstract

Plasma can efficiently inactivate microbial pathogens. Application of plasma on the skin can not only kill bacteria but also change the nature of skin. The influence of plasma jet treatment on the stratum corneum was investigated using the skin of a Yucatan micro pig. Microscopic observation of the histological skin section was used to characterize the etching effect of plasma jet depending on treatment time. Changes in lipid conformations were determined by the bandwidth and absorbance of the symmetric and asymmetric stretching of CH2 and CH3 bands and their ratios using ATR-FTIR spectroscopy. Plasma jet caused structural changes observed via an increase in bandwidth and a decrease in absorbance of the lipid vibrational bands. Plasma effects were saturated after 2 min of treatment. The influence of temperature and UV irradiation was also evaluated. The monitoring of plasma-treated skin demonstrated the temporal effect of changes caused by plasma.

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等离子体放电对猪表皮层结构的影响

血浆可以有效地灭活微生物病原体。在皮肤上使用等离子体不仅可以杀死细菌，还可以改变皮肤的性质。采用尤卡坦微型猪皮肤，研究了等离子体射流处理对角质层的影响。显微观察组织学皮肤切片，表征等离子体射流蚀刻效果随处理时间的变化。通过ATR-FTIR光谱测定CH2和CH3的对称和不对称拉伸的带宽和吸光度及其比值，确定脂质构象的变化。等离子体射流通过脂质振动带的带宽增加和吸光度降低引起结构变化。治疗2分钟后，血浆效应达到饱和。并对温度和紫外线照射的影响进行了评价。对等离子体治疗皮肤的监测显示了等离子体引起的变化的时间效应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plasma Medicine Physics and Astronomy-Physics and Astronomy (all)

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Technology has always played an important role in medicine and there are many journals today devoted to medical applications of ionizing radiation, lasers, ultrasound, magnetic resonance and others. Plasma technology is a relative newcomer to the field of medicine. Experimental work conducted at several major universities, research centers and companies around the world over the recent decade demonstrates that plasma can be used in variety of medical applications. It is already widely used surgeries and endoscopic procedures. It has been shown to control properties of cellular and tissue matrices, including biocompatibility of various substrates. Non-thermal plasma has been demonstrated to deactivate dangerous pathogens and to stop bleeding without damaging healthy tissue. It can be used to promote wound healing and to treat cancer. Understanding of various mechanisms by which plasma can interact with living systems, including effects of reactive oxygen species, reactive nitrogen species and charges, has begun to emerge recently. The aim of the Plasma Medicine journal will be to provide a forum where the above topics as well as topics closely related to them can be presented and discussed. Existing journals on plasma science and technology are aimed for audiences with primarily engineering and science background. The field of Plasma Medicine, on the other hand, is highly interdisciplinary. Some of prospective readers and contributors of the Plasma Medicine journal are expected to have background in medicine and biology. Others might be more familiar with plasma science. The goal of the proposed Plasma Medicine journal is to bridge the gap between audiences with such different backgrounds, without sacrificing the quality of the papers be their emphasis on medicine, biology or plasma science and technology.