Medicinal plants with potential antihypertensive properties: emphasis on natural products from the Brazilian Cerrado

Hoehnea Pub Date : 2022-01-01 DOI:10.1590/2236-8906-123/2020

Marcelo Antônio da Trindade, Fernanda Cardoso da Silva, Bruna Juber de Araújo, J. L. Silva, T. Araújo, C. R. Fürstenau

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Abstract

ABSTRACT Arterial hypertension is a worldwide public health problem and the search for new medicines is one of the biggest challenges for the treatment of this pathology. Secondary metabolites of plants exhibit pharmacological properties of great phyto therapeutic interest. Cerrado is one of the largest biomes in Brazil and research with Cerrado plants as therapeutic resources is of growing interest. Our objective was to compile data regarding the Cerrado plants that already have some of their active compounds described and may potentially be used to treat arterial hypertension. We concluded that flavonoids, tannins, steroids and saponins exhibit important properties to low blood pressure. Thus, the species from Cerrado Brazilian such as pau-paraíba (Simarouba versicolor), pau-santo (Kielmeyera coriacea), abiu-do-cerrado (Pouteria torta), guarandi (Calophyllum brasiliense), bacaba (Oenocarpus bacaba), puçá-amarelo (Mouriri elliptica), fava-de-anta (Dimorphandramollis), murici (Byrsonima crassifolia) and cereja-do-cerrado (Eugenia calycina) are strong candidates for future herbal studies in this field.

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具有潜在降压特性的药用植物:重点介绍来自巴西塞拉多的天然产物

动脉高血压是一个全球性的公共卫生问题，寻找新药是治疗这一病理的最大挑战之一。植物次生代谢物具有重要的植物治疗药理作用。塞拉多是巴西最大的生物群落之一，塞拉多植物作为治疗资源的研究日益引起人们的兴趣。我们的目标是收集有关塞拉多植物的数据，这些植物已经描述了一些活性化合物，可能用于治疗动脉高血压。我们得出的结论是，类黄酮、单宁、类固醇和皂苷对降低血压有重要作用。因此，巴西塞拉多的pau-paraíba (Simarouba versicolor)、paulo -santo (Kielmeyera coriacea)、abiu-do-cerrado (Pouteria torta)、guarandi (Calophyllum brasiliense)、bacaba (Oenocarpus bacaba)、puçá-amarelo (Mouriri elliptica)、fava-de-anta (Dimorphandramollis)、murici (Byrsonima crassifolia)和cereja-do-cerrado (Eugenia calycina)等物种是未来该领域草药研究的有力候选者。

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Hoehnea

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52 weeks