Adipose derived stromal vascular fraction cells therapy in hemophilic arthropathy: A case report.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Derya Güner, Can Eyigör
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引用次数: 0

Abstract

Stromal vascular fraction (SVF) is a heterogeneous collection of cells obtained from adipose tissue through lipoaspiration and is an alter-native intraarticular treatment option, especially in osteoarthritis (OA). The anti-inflammatory and extracellular tissue repair-stimulating properties of SVF increase its effectiveness in regeneration and repair mechanisms. One of the most common symptoms of hemophilia A and B is hemophilic arthropathy (HA). If HA is not adequately managed initially, patients may require major surgery, including total joint arthroplasty. In a 34-year-old male patient who was treated with intraarticular adipose-derived SVF with the diagnosis of hemophilia B and right grade 4 hemophilic knee arthrosis, clinical and radiological scores showed significant improvement in the 3rd month, 6th month, and 1st year controls after the procedure. Intraarticular adipose-derived SVF treatment should be kept in mind as an effective treatment option with minimal invasiveness and few side effects in HA that does not respond to conservative treatments.

脂肪来源间质血管部分细胞治疗血友病关节病:1例报告。
基质血管分数(SVF)是通过吸脂从脂肪组织中获得的异质细胞集合,是一种替代的关节内治疗选择,特别是在骨关节炎(OA)中。SVF的抗炎和刺激细胞外组织修复的特性增加了其在再生和修复机制中的有效性。血友病A和B最常见的症状之一是血友病关节病(HA)。如果HA最初没有得到充分的处理,患者可能需要大手术,包括全关节置换术。一名34岁男性患者接受了关节内脂肪源性SVF治疗,诊断为血友病B和右4级血友病膝关节,手术后第3个月、第6个月和第1年对照的临床和放射学评分显示有显著改善。对于保守治疗无效的HA,应牢记关节内脂肪源性SVF治疗是一种有效的治疗选择,具有最小的侵入性和很少的副作用。
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来源期刊
CiteScore
1.00
自引率
16.70%
发文量
22
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