Does 24-Hour Urine Supersaturation Predict Stone Composition?

World journal of nephrology and urology Pub Date : 2015-04-16 DOI:10.14740/WJNU206W

M. Omar, S. Tarplin, Alla El Deen El Mahdy, M. Monga

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引用次数: 1

Abstract

Background: The aim of the study was to evaluate the correlation between 24-hour urine supersaturation (SS) levels and the crystalline stone composition. Methods: We retrospectively reviewed the results of stone analysis of 386 patients who had completed 24-hour urine stone risk profiles within 2 months of stone analysis. Patients were characterized as calcium oxalate (CAOX), calcium phosphate (CAPH) or uric acid (UA) stone formers based on the predominant component (> 60%) of their stone. Patients with < 50% of one stone composition were characterized as a mixed stone former. Sensitivity, specificity and accuracy of the 24-hour urine SS for predicting the corresponding stone component were calculated. Results: The distribution of stone compositions was 235 (61%) CAOX, 98 (25%) CAPH, 35 (9%) UA and 18 (5%) mixed stone group. At predominant stone mineral concentration ? 60%, the accuracy of 24-hour urine SS for predicting the predominant stone composition was 52.5% for CAOX, 70% for CAPH and 67% for UA group. Even when the predominant stone mineral concentration was ? 90%, the accuracy of SS did not improve: COAX (49%, P = 0.6641), CAPH (77%, P = 0.361) and UA (67%, P = 0.9593). Conclusions: Twenty-four-hour urine SS has a poor accuracy to predict the predominant stone composition. Accuracy is highest for patients with CAPH stones. World J Nephrol Urol. 2015;4(1):169-172 doi: http://dx.doi.org/10.14740/wjnu206w

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24小时尿过饱和度能预测结石成分吗?

背景:本研究的目的是评估24小时尿过饱和度(SS)水平与结晶石组成之间的关系。方法:我们回顾性分析了386例患者的结石分析结果，这些患者在2个月内完成了24小时尿结石风险分析。根据结石的主要成分(bbb60 %)，将患者分为草酸钙(CAOX)、磷酸钙(CAPH)或尿酸(UA)结石患者。一种结石成分< 50%的患者被认为是混合结石。计算24小时尿液SS预测相应结石成分的敏感性、特异性和准确性。结果:结石组成分布为CAOX组235例(61%)，CAPH组98例(25%)，UA组35例(9%)，混合石组18例(5%)。在主要的石矿物浓度?24小时尿液SS预测CAOX组主要结石组成的准确率为52.5%，CAPH组为70%，UA组为67%。即使当主要的石质矿物浓度是?COAX (49%， P = 0.6641)、CAPH (77%， P = 0.361)和UA (67%， P = 0.9593)的准确率均未提高。结论:24小时尿液SS预测主要结石组成的准确性较差。对于有CAPH结石的患者，准确率最高。世界植物学报，2015;4(1):169-172 doi: http://dx.doi.org/10.14740/wjnu206w

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World journal of nephrology and urology

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