A study of the bioactivity, hemocompatibility and antimicrobial properties of a zinc oxide and calcium phosphate composite for bone regeneration

Q3 Materials Science
A. A. Barbosa, S. A. Júnior, A. Ferraz
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引用次数: 0

Abstract

The need for the reconstruction of large bone defects is an issue that arouses great interest in the field of materials science. The development of synthetic grafts similar to bone tissue is a promising option. Thus, this study proposes the synthesis of a zinc oxide and calcium phosphate composite in order to evaluate both its properties and its potential for bone applications. The synthesis of the HAp/TCP@ZnO composite was carried out in two stages; first, the precipitation method was employed. In the second stage, the ZnO was incorporated into the powder produced in the first stage. After the characterization of the material, the presence of HAp in its X-ray diffractogram as the major phase and TCP as the secondary phase was verified; moreover, ZnO peaks were also detected. Tests in a simulated body fluid indicated that the composite was highly bioactive, whereas hemolysis tests confirmed its non-toxicity. The addition of 10.0% of ZnO to the biomaterial provided it with antimicrobial properties.
氧化锌和磷酸钙复合材料骨再生的生物活性、血液相容性和抗菌性能研究
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来源期刊
Cerâmica
Cerâmica Materials Science-Ceramics and Composites
CiteScore
1.90
自引率
0.00%
发文量
37
审稿时长
10 weeks
期刊介绍: A Revista Cerâmica, órgão oficial da Associação Brasileira de Cerâmica (ABCERAM) publica contribuições originais de interesse na área de cerâmica, compreendendo arte cerâmica, abrasivos, biocerâmicas, cerâmicas avançadas, cerâmica branca, cerâmica de mesa, cerâmica eletroeletrônica, cerâmica estrutural, cerâmica magnética, cerâmica nuclear, cerâmica óptica, cerâmica química, cerâmica termomecânica, cerâmica vermelha, cimento, compósitos de matriz cerâmica, materiais refratários, materiais de revestimento, matérias-primas, vidrados, vidros e vitrocerâmicas, análise microestrutural, ciência básica, instrumentação, processos de fabricação, síntese de pós, técnicas de caracterização etc.
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