Major sickle cell disease and pregnancy: about 24 cases observed in a reference structure in Senegal (National hospital of pikine)

IF 2.7 Q2 OBSTETRICS & GYNECOLOGY

Womens Health Pub Date : 2019-01-01 DOI:10.15406/mojwh.2019.08.00257

M. Diallo, A. Diouf, A. Niass, A. Diallo, B. Biaye, Hadja Maimouna Barro Daff, Codou Sene Seck, A. Dia

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引用次数: 1

Abstract

Sickle cell disease is a genotypic condition characterized by the presence of a hemoglobin S which results biologically and clinically suckling red blood cells and hemolytic anemia.1,2 The occurrence of pregnancy in this fragile situation can trigger fearsome maternal and fetal complications even when appropriate preventive measures are used. Management must be multidisciplinary, involving obstetrician, hematologist and pediatrician assisted by different specialists depending on the evolution. Progress in these areas has allowed women to reach reproductive age and even pregnancy with the risk of complications for them and their fetus. For this, early detection of the disease is essential to plan the best time to be pregnant. In view of this context of pregnancy, which deserves great attention, we have decided to conduct a study on the association of major sickle cell disease and pregnancy at the Pikine National Hospital Center. The main objective is to study the management and prognosis of this particularly morbid pathology when it is associated with pregnancy, in the quest to propose a protocol for its management. Patients and methods

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严重镰状细胞病与妊娠:在塞内加尔的一个参考结构中观察到约24例(国立猪医院)

镰状细胞病是一种以血红蛋白S存在为特征的基因型疾病，其生物学和临床结果是哺乳红细胞和溶血性贫血。1,2在这种脆弱的情况下怀孕，即使采取了适当的预防措施，也可能引发可怕的产妇和胎儿并发症。管理必须是多学科的，包括产科医生、血液科医生和儿科医生，由不同的专家根据病情发展协助。在这些领域取得的进展使妇女能够达到生育年龄，甚至怀孕，但她们和胎儿面临并发症的风险。因此，及早发现这种疾病对于计划最佳怀孕时间至关重要。鉴于这种值得高度关注的妊娠情况，我们决定在Pikine国家医院中心开展一项关于重大镰状细胞病与妊娠关系的研究。主要目的是研究与妊娠相关的这种特殊病态病理的管理和预后，以寻求提出其管理方案。患者及方法

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来源期刊

Womens Health OBSTETRICS & GYNECOLOGY-

CiteScore

2.80

自引率

4.20%

发文量

审稿时长

15 weeks

期刊介绍： For many diseases, women’s physiology and life-cycle hormonal changes demand important consideration when determining healthcare management options. Age- and gender-related factors can directly affect treatment outcomes, and differences between the clinical management of, say, an adolescent female and that in a pre- or postmenopausal patient may be either subtle or profound. At the same time, there are certain conditions that are far more prevalent in women than men, and these may require special attention. Furthermore, in an increasingly aged population in which women demonstrate a greater life-expectancy.