Clinical Relevance of Molecular Microbiology

Abstract

Molecular methods for the detection and characterization of microorganisms have transformed diagnostic microbiology. Detection of microorganisms was previously laborious and time taking by conventional microbiological methods but now more rapid detection by molecular methods is possible for pathogens of public health importance. Detection of antimicrobial resistance genes and their characterization by genotyping is also feasible. Detection of viral resistance gene and testing of viral load for the monitoring of antiviral therapies are possible because of molecular technique and automation of molecular microbiology. This review will focus on basic molecular techniques and the clinical utility of these molecular methods in the management of infectious diseases.