Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture

IF 0.2 Q4 CHEMISTRY, MULTIDISCIPLINARY

Revista Colombiana de Quimica Pub Date : 2016-09-01 DOI:10.15446/REV.COLOMB.QUIM.V45N3.58085

Oman Zuas, Muhammad Rizky Mulyana, H. Budiman

{"title":"Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture","authors":"Oman Zuas, Muhammad Rizky Mulyana, H. Budiman","doi":"10.15446/REV.COLOMB.QUIM.V45N3.58085","DOIUrl":null,"url":null,"abstract":"An accurate gas chromatography coupled to a flame ionization detector (GC-FID) method was validated for the simultaneous analysis of light hydrocarbons (C 2 -C 4 ) in their gas mixture. The validation parameters were evaluated based on the ISO/IEC 17025 definition including method selectivity, repeatability, accuracy, linearity, limit of detection (LOD), limit of quantitation (LOQ), and ruggedness. Under the optimum analytical conditions, the analysis of gas mixture revealed that each target component was well-separated with high selectivity property. The method was also found to be precise and accurate. The method linearity was found to be high with good correlation coefficient values (R 2 ≥ 0.999) for all target components. It can be concluded that the GC-FID developed method is reliable and suitable for determination of light C 2 -C 4 hydrocarbons (including ethylene, propane, propylene, isobutane, and n-butane) in their gas mixture. The validated method has successfully been applied to the estimation of hydrocarbons light C 2 -C 4 hydrocarbons in natural gas samples, showing high performance repeatability with relative standard deviation (RSD) less than 1.0% and good selectivity with no interference from other possible components could be observed.","PeriodicalId":43662,"journal":{"name":"Revista Colombiana de Quimica","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Colombiana de Quimica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15446/REV.COLOMB.QUIM.V45N3.58085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 4

Abstract

An accurate gas chromatography coupled to a flame ionization detector (GC-FID) method was validated for the simultaneous analysis of light hydrocarbons (C 2 -C 4 ) in their gas mixture. The validation parameters were evaluated based on the ISO/IEC 17025 definition including method selectivity, repeatability, accuracy, linearity, limit of detection (LOD), limit of quantitation (LOQ), and ruggedness. Under the optimum analytical conditions, the analysis of gas mixture revealed that each target component was well-separated with high selectivity property. The method was also found to be precise and accurate. The method linearity was found to be high with good correlation coefficient values (R 2 ≥ 0.999) for all target components. It can be concluded that the GC-FID developed method is reliable and suitable for determination of light C 2 -C 4 hydrocarbons (including ethylene, propane, propylene, isobutane, and n-butane) in their gas mixture. The validated method has successfully been applied to the estimation of hydrocarbons light C 2 -C 4 hydrocarbons in natural gas samples, showing high performance repeatability with relative standard deviation (RSD) less than 1.0% and good selectivity with no interference from other possible components could be observed.

查看原文本刊更多论文

GC-FID同时测定其气体混合物中碳氢化合物(C2-C4)的分析方法验证

验证了气相色谱-火焰离子化检测器(GC-FID)的同时分析轻烃(c2 - c4)的方法。根据ISO/IEC 17025定义对验证参数进行评估，包括方法选择性、可重复性、准确性、线性度、检出限(LOD)、定量限(LOQ)和耐用性。在最佳分析条件下，混合气体的分析表明，各目标组分分离良好，具有较高的选择性。该方法也被证明是精确和准确的。结果表明，该方法线性度高，各目标成分的相关系数均较好(r2≥0.999)。结果表明，该方法可靠，适用于轻碳氢化合物(包括乙烯、丙烷、丙烯、异丁烷和正丁烷)混合物的测定。该方法已成功应用于天然气样品中碳氢化合物轻碳氢化合物c2 - c4的估计，具有较高的重复性，相对标准偏差(RSD)小于1.0%，选择性好，不受其他可能组分的干扰。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista Colombiana de Quimica CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： The Revista Colombiana de Química - Colombian Journal of Chemistry (Rev. Colomb. Quim.) Is a peer-reviewed scientific journal of the Department of Chemistry, Faculty of Sciences of the Universidad Nacional de Colombia, Bogotá. It currently publishes three volumes per year: January-April, May-August and September-December. All the content published by the Journal (available online) is under a Creative Commons attribution license type BY 4.0, that allows any person or entity in the world to freely access the content, share it, download it, adapt it or make derivative works without any restriction, provided that it adequately indicates the credit to the authors and to the Colombian Journal of Chemistry.