Diagnosis and treatment of central diabetes insipidus

Q3 Medicine

Obesity and Metabolism Pub Date : 2014-11-18 DOI:10.14341/OMET2014448-55

E. Pigarova, L. Dzeranova

引用次数: 12

Abstract

Diabetes insipidus represents a serious disease that dramatically interferes with the everyday life of patients due to the need to constantly replenish of fluid lost in the urine, which comes amid shortage of synthesis, secretion or action of pituitary hormone vasopressin. The main difficulty is the differential diagnosis of types of diabetes insipidus in patients with the syndrome of polydipsia-polyuria as the correct differential diagnosis of these forms predetermine the safety and efficacy of further treatment. This lecture presents the current concepts of etiology, diagnosis and treatment of central diabetes insipidus (CDI). We give the comparative characteristics of various preparations of desmopressin for the treatment of the central form of the disease. We also consider the features of the management of selected patient populations with CDI: during pregnancy and lactation, pathology of the thirst sensation, after traumatic brain injury and neurosurgery.

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中枢性尿崩症的诊断与治疗

尿崩症是一种严重的疾病，由于需要不断补充尿中流失的液体，这是由于垂体激素抗利尿激素的合成、分泌或作用不足而导致的。多饮多尿综合征患者尿崩症类型的鉴别诊断是主要的难点，因为这些类型的正确鉴别诊断预先决定了进一步治疗的安全性和有效性。本讲座介绍中枢性尿崩症(CDI)的病因、诊断及治疗的最新概念。我们给去氨加压素的治疗中心形式的疾病的各种制剂的比较特点。我们还考虑了选定的CDI患者群体的管理特点:在怀孕和哺乳期间，口渴感觉的病理，创伤性脑损伤和神经外科手术后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obesity and Metabolism Medicine-Internal Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Journal "Obesity and Metabolism" is a multidisciplinary forum for clinical and applied research in the field of biochemistry, physiology, pathophysiology, genetics, nutrition, as well as molecular, metabolic, psychological and epidemiological aspects of obesity and metabolism. The main subject "Metabolism" reviewed in the journal, includes fat, carbohydrate, protein, bone, fluid and electrolyte and other types of metabolism in the spectrum of pathology of the endocrine system. The priority direction of Journal "Obesity and Metabolism" is publishing modern high-quality original research on the effectiveness of new and existing treatments in any aspect of metabolic and endocrine diseases. Pre-clinical pharmacology, pharmacokinetics studies, meta-analyzes, addressed to drug safety and tolerance are also welcome for publication in the journal "Obesity and metabolism." Journal "Obesity and Metabolism" announces review articles that are balanced, clear and offer the reader a modern and critical analysis of the literature on the subject of the magazine. Case reports, and lecture materials are also published for highlighting for practitioners new approaches to diagnosis and treatment of patients with metabolic disorders and obesity.