{"title":"Changes in Brain Perfusion in Patients with Unilateral Lower-limb Paresis, before and after Training on a Pedaling Wheelchair: A Feasibility Study","authors":"T. Sekiya, K. Seki, Y. Handa","doi":"10.14326/ABE.8.99","DOIUrl":null,"url":null,"abstract":"Our aim was to evaluate the effects of a 4-week training program using a self-powered pedaling wheelchair on brain perfusion in patients presenting with lower limb hemiparesis due to stroke, brain injury, or spinal cord injury. Our cross-sectional observational study included seven patients with lower limb hemiparesis ( ve men, two women; mean age, 68.3 ± 17.5 years), due to the following causes: cerebral hemorrhage (n = 1), stroke (n = 4), brain contusion (n = 1), and spinal cord injury (n = 1). The control group consisted of eight healthy participants (3 men, 5 women; mean age 62 ± 8 years). The training program consisted of ve bouts of 3-min continuous pedaling per day (total, 15 min/day). The outcome variable of interest was blood ow velocity in the middle cerebral artery (time average peak [TAP], cm/s) measured using Doppler. TAP was measured at rest and after a 3-min pedaling bout, before and after the training program. In the patient group, TAP was signi cantly greater after the 3-min bout than at rest, both before and after the training program (p < 0.05). There was no effect of pedaling identi ed in the control group. In the patient group, TAP increased signi cantly (p < 0.05) after training, both at rest (36.9 ± 16.9 to 47.6 ± 13.8 cm/s), and after the 3-min bout (43.3 ± 13.3 to 50.5 ± 15.1 cm/s). Our pedaling wheelchair provided a safe and effective intervention to improve brain perfusion in this patient population.","PeriodicalId":54017,"journal":{"name":"Advanced Biomedical Engineering","volume":"1 1","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Biomedical Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14326/ABE.8.99","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Our aim was to evaluate the effects of a 4-week training program using a self-powered pedaling wheelchair on brain perfusion in patients presenting with lower limb hemiparesis due to stroke, brain injury, or spinal cord injury. Our cross-sectional observational study included seven patients with lower limb hemiparesis ( ve men, two women; mean age, 68.3 ± 17.5 years), due to the following causes: cerebral hemorrhage (n = 1), stroke (n = 4), brain contusion (n = 1), and spinal cord injury (n = 1). The control group consisted of eight healthy participants (3 men, 5 women; mean age 62 ± 8 years). The training program consisted of ve bouts of 3-min continuous pedaling per day (total, 15 min/day). The outcome variable of interest was blood ow velocity in the middle cerebral artery (time average peak [TAP], cm/s) measured using Doppler. TAP was measured at rest and after a 3-min pedaling bout, before and after the training program. In the patient group, TAP was signi cantly greater after the 3-min bout than at rest, both before and after the training program (p < 0.05). There was no effect of pedaling identi ed in the control group. In the patient group, TAP increased signi cantly (p < 0.05) after training, both at rest (36.9 ± 16.9 to 47.6 ± 13.8 cm/s), and after the 3-min bout (43.3 ± 13.3 to 50.5 ± 15.1 cm/s). Our pedaling wheelchair provided a safe and effective intervention to improve brain perfusion in this patient population.