A severe case of cutaneous squamous cell carcinoma keratoacanthoma type in a 55-year-old man

Abstract

Cutaneous squamous cell carcinoma (SCC) is the second most common nonmelanoma skin cancer. The clinical features of SCC typically include scaly, crusted, nonhealing, ulcerative lesions in sun-exposed areas of the body. We present here the interesting case of a patient who was diagnosed with extremely severe SCC, keratoacanthoma-type (KA; SCC-KA type) with multiple annular, crusted, papular lesions (8-20 mm) on the dorsal aspect of his hands and forearms. The patient was successfully treated with cetuximab over 78 days, with complete resolution.