Early Mobilization in Critically Ill Patients

Abstract

Mortality in the ICU has dramatically decreased over the past decades because of a clearer understanding of disease pathophysiology, improved technology, and novel therapies. This success has led to the new challenge of treating patients with chronic disabilities resulting from prolonged ICU stays. In this review, the authors (a) describe the emerging understanding of the basis for ICU-acquired weakness, including contributing factors such as prolonged bed rest; (b) provide the background for the safety and efficacy of early mobilization; and (c) give practical guidance for the implementation of ICU early mobilization based on their experience over the past 8 years.