M. Camacho, S. Zaghi, D. Tran, Sungjin A. Song, Edward T. Chang, V. Certal
{"title":"Inferior Turbinate Size and CPAP Titration Based Treatment Pressures: No Association Found among Patients Who Have Not Had Nasal Surgery","authors":"M. Camacho, S. Zaghi, D. Tran, Sungjin A. Song, Edward T. Chang, V. Certal","doi":"10.1155/2016/5951273","DOIUrl":null,"url":null,"abstract":"Objective. To evaluate the effect of turbinate sizes on the titrated continuous positive airway pressure (CPAP) therapeutic treatment pressures for patients with obstructive sleep apnea (OSA) who have not had nasal surgery. Study Design. Retrospective case series. Methods. A chart review was performed for 250 consecutive patients. Results. 45 patients met inclusion criteria. The mean ± standard deviation (M ± SD) for age was 54.6 ± 22.4 years and for body mass index was 28.5 ± 5.9 kg/m2. The Spearman's rank correlation coefficient (r s) between CPAP therapeutic treatment pressures and several variables were calculated and were weakly correlated (age r s = 0.29, nasal obstruction r s = −0.30), moderately correlated (body mass index r s = 0.42 and lowest oxygen saturation r s = −0.47), or strongly correlated (apnea-hypopnea index r s = 0.60 and oxygen desaturation index (r s = 0.62)). No statistical significance was found with one-way analysis of variance (ANOVA) between CPAP therapeutic treatment pressures and inferior turbinate size (right turbinates p value = 0.2012, left turbinate p value = 0.3064), nasal septal deviation (p value = 0.4979), or mask type (p value = 0.5136). Conclusion. In this study, CPAP titration based therapeutic treatment pressures were not found to be associated with inferior turbinate sizes; however, the CPAP therapeutic treatment pressures were strongly correlated with apnea-hypopnea index and oxygen desaturation index.","PeriodicalId":32361,"journal":{"name":"International Journal of Otolaryngology","volume":"2016 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/5951273","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Otolaryngology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2016/5951273","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
Objective. To evaluate the effect of turbinate sizes on the titrated continuous positive airway pressure (CPAP) therapeutic treatment pressures for patients with obstructive sleep apnea (OSA) who have not had nasal surgery. Study Design. Retrospective case series. Methods. A chart review was performed for 250 consecutive patients. Results. 45 patients met inclusion criteria. The mean ± standard deviation (M ± SD) for age was 54.6 ± 22.4 years and for body mass index was 28.5 ± 5.9 kg/m2. The Spearman's rank correlation coefficient (r s) between CPAP therapeutic treatment pressures and several variables were calculated and were weakly correlated (age r s = 0.29, nasal obstruction r s = −0.30), moderately correlated (body mass index r s = 0.42 and lowest oxygen saturation r s = −0.47), or strongly correlated (apnea-hypopnea index r s = 0.60 and oxygen desaturation index (r s = 0.62)). No statistical significance was found with one-way analysis of variance (ANOVA) between CPAP therapeutic treatment pressures and inferior turbinate size (right turbinates p value = 0.2012, left turbinate p value = 0.3064), nasal septal deviation (p value = 0.4979), or mask type (p value = 0.5136). Conclusion. In this study, CPAP titration based therapeutic treatment pressures were not found to be associated with inferior turbinate sizes; however, the CPAP therapeutic treatment pressures were strongly correlated with apnea-hypopnea index and oxygen desaturation index.
目标。评估鼻甲大小对未做过鼻手术的阻塞性睡眠呼吸暂停(OSA)患者滴定持续气道正压通气(CPAP)治疗压力的影响。研究设计。回顾性病例系列。方法。对连续250例患者进行了图表回顾。结果:45例患者符合纳入标准。年龄的平均值±标准差(M±SD)为54.6±22.4岁,体重指数为28.5±5.9 kg/m2。计算CPAP治疗压力与多个变量之间的Spearman等级相关系数(r s),相关性为弱相关(年龄r s = 0.29,鼻塞r s = - 0.30),中度相关(体重指数r s = 0.42,最低氧饱和度r s = - 0.47),或强相关(呼吸暂停-低通气指数r s = 0.60,氧去饱和指数r s = 0.62)。CPAP治疗压力与下鼻甲大小(右鼻甲p值= 0.2012,左鼻甲p值= 0.3064)、鼻中隔偏曲(p值= 0.4979)、口罩类型(p值= 0.5136)之间的单因素方差分析(ANOVA)无统计学意义。结论。在本研究中,基于CPAP滴定的治疗压力未发现与下鼻甲大小相关;然而,CPAP治疗压力与呼吸暂停低通气指数和氧去饱和指数密切相关。