PhD Claire André, PhD Elizabeth Kuhn, PhD Stéphane Rehel, PhD Valentin Ourry, Solène Demeilliez-Servouin MSc, MSc Cassandre Palix, MSc Francesca Felisatti, MSc Pierre Champetier, MD Sophie Dautricourt, PhD Paul Yushkevich, Denis, V. De, MD La Sayette, PhD Gaël Chételat, PhD Robin de Flores, G. Rauchs, MD Andrea Schneider
{"title":"Neurology","authors":"PhD Claire André, PhD Elizabeth Kuhn, PhD Stéphane Rehel, PhD Valentin Ourry, Solène Demeilliez-Servouin MSc, MSc Cassandre Palix, MSc Francesca Felisatti, MSc Pierre Champetier, MD Sophie Dautricourt, PhD Paul Yushkevich, Denis, V. De, MD La Sayette, PhD Gaël Chételat, PhD Robin de Flores, G. Rauchs, MD Andrea Schneider","doi":"10.1136/jnnp.s1-17.65.80","DOIUrl":null,"url":null,"abstract":"Background and objectives: Sleep-disordered breathing (SDB) has been related to amyloid deposition and increased dementia risk. However, how SDB relates to medial temporal lobe neurodegeneration and subsequent episodic memory impairment is unclear. Our objective was to investigate the impact of amyloid positivity on the associations between SDB severity, medial temporal lobe subregions and episodic memory performance in cognitively unimpaired older adults.","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1936-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-17.65.80","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurology and Psychopathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/jnnp.s1-17.65.80","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background and objectives: Sleep-disordered breathing (SDB) has been related to amyloid deposition and increased dementia risk. However, how SDB relates to medial temporal lobe neurodegeneration and subsequent episodic memory impairment is unclear. Our objective was to investigate the impact of amyloid positivity on the associations between SDB severity, medial temporal lobe subregions and episodic memory performance in cognitively unimpaired older adults.
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