A clinical evaluation of Azithromycin and questionnaire survey in patients with acute dental infection

Q4 Pharmacology, Toxicology and Pharmaceutics
N. Terakado, S. Shintani, S. Hara, H. Shinohara, Junya Yano, H. Kayahara, K. Nakashiro, S. Hino, H. Hamakawa
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Abstract

The efficacy of azithromycin as a chemoprophylactic agent for acute dental infection was assessed, and a questionnaire survey about the impression of azithromycin was conducted. METHODS: Eighty-three patients were given 500 mg of azithromycin for three days. Seven days after the onset of the treatment, we evaluated the clinical symptoms and collected the questionnaires. RESULTS: Clinical efficacy was observed in 89.2% of the patients, and that by questionnaire was 86.7%. Diarrhea as a side effect was seen in two patients. In the questionnaire, 79% of patients noted its effect from the second to fourth day after the medication. Although half of the patients did not care about the convenience, of taking the medication once a day, which is one of the advantages of azithromycin, most of the patients were satisfied with its efficacy. Furthermore, 72.3% of patients considered azithromycin to be significantly more acceptable compared with other antibiotics. CONCLUSION : Azithromycin is a useful therapeutic regimen for the treatment of acute dental infections.
阿奇霉素在急性口腔感染患者中的临床评价及问卷调查
评价阿奇霉素作为化学预防药物治疗急性口腔感染的疗效,并对患者对阿奇霉素的印象进行问卷调查。方法:83例患者给予阿奇霉素500 mg,连续3天。在治疗开始后7天,我们评估患者的临床症状并收集问卷。结果:临床有效率为89.2%,问卷调查有效率为86.7%。两名患者出现腹泻的副作用。在调查问卷中,79%的患者在服药后的第二到第四天注意到其效果。虽然有一半的患者并不关心阿奇霉素的优点之一,即每天服药一次是否方便,但大多数患者对其疗效感到满意。此外,72.3%的患者认为阿奇霉素比其他抗生素更容易接受。结论:阿奇霉素是治疗急性口腔感染的有效治疗方案。
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来源期刊
Oral Therapeutics and Pharmacology
Oral Therapeutics and Pharmacology Medicine-Pharmacology (medical)
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