Characterizing artefact in the normal human 24-hour RR time series to aid identification and artificial replication of circadian variations in human beat to beat heart rate using a simple threshold

Gari D Clifford, P. McSharry, L. Tarassenko
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引用次数: 73

Abstract

The authors present an investigation into the incidences of ectopy and artefact as a function of time of day, heart rate and state changes for 19 normal subjects. State changes are defined to be a statistically significant change in mean or variance over a window of a few minutes. Artefact incidence is shown to be significantly correlated with state change and heart rate in normal humans, whereas ectopy exhibits no significant relationship. Artefact is therefore shown to be a source of information which can aid identification of activity or state changes and facilitate abnormality detection inpatient populations. Timing thresholds are proposed which differentiate between artefact, ectopy and sinus beats. A classification system based upon the frequency of artefact occurrences in relation to state changes is presented which correctly separates 78% of the the real (normal) and artificial RR interval time series in event 2 of the CinC Challenge 2002 (entry number 38).
表征正常人类24小时RR时间序列中的伪影,以帮助识别和人工复制人类搏动到搏动心率的昼夜变化,使用简单的阈值
作者对19名正常受试者的宫外孕和人工造影术的发生率与时间、心率和状态变化的关系进行了调查。状态变化被定义为在几分钟的窗口内平均或方差的统计显著变化。在正常人群中,伪影发生率与状态变化和心率显著相关,而异位则无显著关系。因此,人工产物被证明是一种信息来源,可以帮助识别活动或状态变化,并促进对住院患者群体的异常检测。提出了区分伪影、异位和窦性搏动的时间阈值。提出了一种基于与状态变化相关的人工事件发生频率的分类系统,该系统在2002年CinC挑战赛(参赛编号38)的事件2中正确分离了78%的真实(正常)和人工RR间隔时间序列。
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