Perioperative Assessment and Risk Management in Patients With Obstructive Sleep Apnea

E. Seet, F. Chung
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Abstract

Author Disclosure Information: Dr. Seet has disclosed that he has no financial interests in or significant relationship with any commercial companies pertaining to this educational activity. Dr. Chung has disclosed that she receives funding for research from Pfizer, the ResMed Foundation, and the Respironic Foundation. Obstructive sleep apnea (OSA) is a clinical syndrome defined by repetitive partial or complete upper airway obstruction, characterized by episodes of breathing cessation during sleep lasting 10 or more seconds. The inherent pharyngeal collapsibility due to depression of pharyngeal muscle regulation during sleep and anesthesia predisposes to impaired respiration. Recurring airway obstruction causes repeated arousals and increased sympathetic output, cumulating in daytime hypersomnolence, memory loss, executive dysfunction, and other psychological disturbances.
阻塞性睡眠呼吸暂停患者围手术期评估及风险管理
作者披露信息:Seet博士已披露,他在与此教育活动有关的任何商业公司中没有经济利益或重大关系。钟博士透露,她接受辉瑞公司、瑞思迈基金会和呼吸器基金会的研究资助。阻塞性睡眠呼吸暂停(OSA)是一种重复性部分或完全上呼吸道阻塞的临床综合征,其特征是睡眠中呼吸停止发作持续10秒或更长时间。由于睡眠和麻醉时咽肌调节的抑制,固有的咽部折叠性易导致呼吸受损。反复出现的气道阻塞引起反复觉醒和交感神经输出增加,在白天嗜睡、记忆丧失、执行功能障碍和其他心理障碍中积累。
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