Limitations of whole-body irradiation for inducing acceptance of homografts in cases involving a genetic defect.

Abstract

Experiments are described and discussed in which normal isologous and homologous hematopoietic tissue implants in genetically anemic mice were exposed to various doses of x rays. The findings suggest considerable limitation to the use of radiation in inducing acceptance of homografts in mice or humans with specific genetic defects. (T.R.H.)