{"title":"Transplant Kidney With Acute Humoral Rejection Diagnosed by Needle Core Biopsy—A Case Report With Review of Pathological Morphology","authors":"J. Aufman","doi":"10.1097/PCR.0000000000000112","DOIUrl":null,"url":null,"abstract":"Abstract Needle core biopsy is an important procedure used to evaluate transplanted kidneys. By examining the morphological findings, the pathologist can inform the nephrologist of certain findings that help guide the therapeutic management to prolong the life of the transplant kidney. The request for a kidney biopsy is usually decided as soon as signs and symptoms of renal dysfunction are noticed by the nephrologist, and therefore, most biopsies of the transplanted kidneys usually have some type of morphological pathology, which may be minimal because of the acute awareness of early rejection. This review discusses the history of acute antibody-mediated rejection and the morphological findings seen in humor rejection of the transplanted kidney.","PeriodicalId":43475,"journal":{"name":"AJSP-Reviews and Reports","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/PCR.0000000000000112","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"AJSP-Reviews and Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/PCR.0000000000000112","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Needle core biopsy is an important procedure used to evaluate transplanted kidneys. By examining the morphological findings, the pathologist can inform the nephrologist of certain findings that help guide the therapeutic management to prolong the life of the transplant kidney. The request for a kidney biopsy is usually decided as soon as signs and symptoms of renal dysfunction are noticed by the nephrologist, and therefore, most biopsies of the transplanted kidneys usually have some type of morphological pathology, which may be minimal because of the acute awareness of early rejection. This review discusses the history of acute antibody-mediated rejection and the morphological findings seen in humor rejection of the transplanted kidney.
期刊介绍:
Each issue of Pathology Case Reviews examines one vital theme in the field with peer-reviewed, clinically oriented case reports that focus on diagnosis, specimen handling and reports generation. Each theme-oriented issue covers both histopathologic and cytopathologic cases, offering a comprehensive perspective that includes editorials and review articles of the newest developments in the field, differential diagnosis hints, applications of new technologies, reviews of current issues and techniques and an emphasis on new approaches.