Prevention of Rh isoimmunization.

Abstract

The simple measure of giving Rh-negative mothers of Rh-positive, A B o-compatible infants a few micrograms of anti-Rh gamma globulin after delivery has already reduced the incidence of erythroblastosis fetalis enormously and promises to make it a rare disease in the near future. The underlying concepts and clinical experience leading to the institution of Rh prophylaxis for all mothers at risk are described.