Treatment of mature striae with the pulsed dye laser.

K. Nehal, Daniel A Lichtenstein, H. Kamino, V. Levine, R. Ashinoff, Ronald O. Perelman
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引用次数: 25

Abstract

INTRODUCTION Striae are a common cosmetic problem with no effective treatment options. A recent study has shown improvement in the appearance of mature striae following a single 585-nm pulsed dye laser (PDL) treatment at low fluence. OBJECTIVE To evaluate the effectiveness of treating mature striae with the 585-nm PDL. METHODS Five patients with mature striae on the abdomen were prospectively treated with the 585-nm PDL at 2-month intervals for 1-2 years. The response of the striae to laser treatment was evaluated in each patient through sequential clinical, photographic, textural, and histologic assessment. RESULTS All five patients reported a slight overall improvement in the appearance of the striae following multiple PDL treatments. Comparison of pre- and post-treatment photographs, however, failed to reveal improvement in any patients. Optical profilometry performed on striae impressions showed mild improvement in the surface texture of striae in three patients. Histologic comparison of pre- and post-treatment biopsy specimens failed to reveal normalization of skin architecture. CONCLUSIONS Serial treatment of mature striae with the PDL results in mild, subjective, clinical improvement but no significant photographic, textural or histologic improvement.
脉冲染料激光处理成熟条纹。
条纹是一种常见的美容问题,没有有效的治疗方法。最近的一项研究表明,在单次585纳米脉冲染料激光(PDL)低通量处理后,成熟条纹的外观有所改善。目的评价585 nm PDL治疗成熟条纹的疗效。方法5例腹部成熟纹行585 nm PDL治疗,间隔2个月,治疗1 ~ 2年。通过连续的临床、摄影、纹理和组织学评估每位患者对激光治疗的反应。结果所有5例患者均报告在多次PDL治疗后,条纹外观略有改善。然而,对比治疗前和治疗后的照片,没有发现任何患者的改善。光学轮廓术进行纹印显示轻度改善表面纹理纹在三个病人。治疗前和治疗后活检标本的组织学比较未能显示皮肤结构的正常化。结论用PDL连续治疗成熟纹可获得轻微的主观临床改善,但在影像学、肌理和组织学上无明显改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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