Selective non-ablative wrinkle reduction by laser

P. Bjerring, Henrik Egevist, M. Clement, L. Heickendorff, M. Kiernan
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引用次数: 175

Abstract

BACKGROUND AND OBJECTIVES: Skin resurfacing and wrinkle removal is a large medical laser market. However, the rate of undesirable side effects is high and sometimes is not warranted by the aesthetic improvement observed. The authors have evaluated the potential benefits of an approach to selective non-ablative wrinkle reduction. MATERIALS AND METHODS: This technique selectively targets the microvasculature which plays a key role in the stimulation of enhanced collagen production. RESULTS: The study reported shows that application of the laser parameters described enhances collagen production by an average of 84%, measured 72 hours after a single laser treatment. This is achieved whilst leaving the skin barrier intact and with no adverse pigmentary changes. The study further shows that a cosmetic improvement is observed with an average value of 1.88 reduction in wrinkle appearance as measured on the Fitzpatrick Wrinkle Severity scale. This improvement was achieved with one brief treatment and no reported incidence of side effects. CONCLUSION: In conclusion, the treatment modality described may be a new approach to the treatment of wrinkles.
激光选择性非烧蚀除皱
背景与目的:皮肤修复和除皱是一个巨大的医疗激光市场。然而,不良副作用的发生率很高,有时观察到的美学改善并不保证。作者已经评估了一种选择性非烧蚀减皱方法的潜在益处。材料和方法:该技术选择性地靶向微血管,在促进胶原蛋白生成的刺激中起关键作用。结果:该研究报告表明,应用激光参数所描述的胶原蛋白产量提高平均84%,测量单次激光治疗后72小时。这是在保持皮肤屏障完整的同时实现的,没有不利的色素变化。研究进一步表明,在菲茨帕特里克皱纹严重程度量表上,皱纹外观的平均减少值为1.88。这种改善是通过一次短暂的治疗实现的,没有副作用的报道。结论:所述的治疗方式可能是治疗皱纹的新途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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