Age and noise-induced hearing loss

E. Toppila, I. Pyykkö, J. Starck
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引用次数: 96

Abstract

The purpose of the study was to evaluate the effect of noise, age and confounders in noise-induced hearing loss (NIHL). Information about work exposure, the use of hearing protective devices, audiogram, environmental and biological factors was collected from 406 paper mill workers exposed to noise levels of 91-94 dB(A), 124 forest workers exposed to noise levels of 96-99 dB(A) and 176 shipyard workers exposed to noise levels 95-97 dB(A). In addition to noise exposure, we collected the following confounders: smoking habits, serum cholesterol, systolic or diastolic blood pressure and use of analgesics. Subjects were classified based on median values, into high- and low-risk groups. The confounders were a significant source of hearing loss (HL) in younger and elderly groups of subjects, serum cholesterol level being the most important. In risk analysis the confounders partly masked the effects of noise in the development of HL. For subjects with less than two confounders, occupational noise exposure determined the development of NIHL. As the number of confounders increased, the noise exposure was overruled by these factors in the development of HL. In analysis where the subjects were matched with pairs by age, exposure, blood pressure and serum cholesterol level, the elderly subjects were more susceptible to NIHL than younger subjects. Factors independently but causally related to age were important in the development of NIHL among workers exposed to noise levels below 98 dB(A).
年龄与噪音引起的听力损失
本研究的目的是评价噪声、年龄和混杂因素对噪声性听力损失(NIHL)的影响。收集了406名91 ~ 94 dB(A)噪声水平造纸厂工人、124名96 ~ 99 dB(A)噪声水平森林工人和176名95 ~ 97 dB(A)噪声水平造船厂工人的工作暴露、听力保护装置使用情况、听力图、环境和生物因素等信息。除了噪音暴露外,我们还收集了以下混杂因素:吸烟习惯、血清胆固醇、收缩压或舒张压以及止痛药的使用。受试者根据中位数分为高风险组和低风险组。这些混杂因素是年轻人和老年人听力损失(HL)的重要来源,血清胆固醇水平是最重要的。在风险分析中,混杂因素部分掩盖了噪声在HL发展中的影响。对于少于两个混杂因素的受试者,职业性噪声暴露决定了NIHL的发展。随着混杂因素数量的增加,噪声暴露在HL的发展中被这些因素所取代。在按年龄、暴露、血压和血清胆固醇水平进行配对的分析中,老年人比年轻人更容易患NIHL。在暴露于低于98 dB(A)噪声水平的工人中,与年龄相关的独立但有因果关系的因素在NIHL的发展中很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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