Epidemiology of pediatric urolithiasis

K. Sarıca, C. Cetinel
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Abstract

Abstract Pediatric urolithiasis is an endemic disease in certain parts of the world, namely Turkey and the Far East. As a recurrent pathology which may reveal functional as well and morphologic changes in the urinary tract, environmental factors together with urogenital abnormalities should be evaluated thoroughly in each patient. The aims of management should be complete clearance of stones, treatment of urinary tract infections, and preservation of renal function and prevention of stone recurrence. In addition to certain minimally invasive stone removal procedures, treatment of pediatric urolithiasis requires a detailed metabolic evaluation in all patients on an individual basis. Obstructive pathologies have to be corrected immediately and children with a positive family history should be followed carefully with respect to a high likelihood of stone re-growth and recurrence. Although specific management of each metabolic abnormality seems to be the key factor in the medical management of stone disease, as general advice each child should be forced to adequate fluid intake which will reveal the urine volume increase in accordance with the body mass index. Moreover, medical therapeutic agents that increase urine citrate levels should be encouraged.
小儿尿石症的流行病学
小儿尿石症是世界上某些地区的地方病,即土耳其和远东地区。作为一种复发性病理,它可以揭示尿路的功能和形态变化,环境因素连同泌尿生殖系统异常应在每个患者中进行彻底的评估。治疗的目的应是彻底清除结石,治疗尿路感染,保护肾功能和预防结石复发。除了某些微创结石移除手术外,儿童尿石症的治疗需要对所有患者进行详细的个体代谢评估。梗阻性病变必须立即纠正,有阳性家族史的儿童应仔细随访,因为结石再生长和复发的可能性很高。虽然每种代谢异常的具体管理似乎是结石疾病医疗管理的关键因素,但一般建议每个孩子都应该强制摄入足够的液体,这将显示尿量根据体重指数增加。此外,应鼓励使用增加尿液柠檬酸盐水平的药物治疗药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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