Drugs able to prevent chronic pain

Grisell Vargas-Schaffer MD
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引用次数: 1

Abstract

Using drugs that follow anatomical pathways and act on receptors to treat acute pain and prevent its transformation into chronic pain is an appealing idea. The challenge consists of providing personalized treatment based on risk factors, pain and surgery type, and the type of rehabilitation program to minimize complications and optimize the pain treatment to prevent chronic pain. Clinical practice has started to understand the pathophysiological mechanisms and various neurochemical receptors involved in the transformation of acute pain into chronic pain. Unfortunately, the clinical reality differs greatly from the theory and no studies based on medical evidence show that using drugs to prevent chronic pain is a real possibility, nor what kinds of pain can actually be prevented with the use of preventive drugs. This article examines what kinds of pain are most commonly referred to chronic pain centers, looks at which drugs can be used to prevent chronic pain, and aims to establish a preventive treatment algorithm based on the type of postoperative pain. There is growing interest in providing therapeutic patient education, which consists of health professionals transferring knowledge to patients. In the model proposed in this article, therapeutic patient education acts as a connecting thread to different factors and enables patients to become more responsible for and proactive in the healing process. Prevention should be comprehensive, and not just pharmacologic.

能够预防慢性疼痛的药物
使用遵循解剖学途径并作用于受体的药物来治疗急性疼痛并防止其转变为慢性疼痛是一个吸引人的想法。挑战包括根据风险因素、疼痛和手术类型以及康复计划的类型提供个性化治疗,以最大限度地减少并发症并优化疼痛治疗以预防慢性疼痛。临床实践已经开始了解急性疼痛转化为慢性疼痛的病理生理机制和各种神经化学受体。不幸的是,临床现实与理论大不相同,没有基于医学证据的研究表明,使用药物来预防慢性疼痛是一种真正的可能性,也没有哪种疼痛实际上可以通过使用预防药物来预防。本文探讨了慢性疼痛中心最常提到的疼痛类型,以及可以使用哪些药物来预防慢性疼痛,并旨在建立基于术后疼痛类型的预防性治疗算法。人们对提供治疗性患者教育越来越感兴趣,这包括卫生专业人员向患者传授知识。在本文提出的模型中,治疗性患者教育作为连接不同因素的纽带,使患者在治疗过程中变得更加负责和主动。预防应该是全面的,而不仅仅是药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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