Malaria: failure, puzzle, challenge.

D. Epstein
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引用次数: 9

Abstract

The fight against Malaria, one of the most complex health problems in the 20th century, is said to be a failure, a puzzle and a challenge. The fight is a failure because the WHO worldwide eradication program that began in 1956 never achieved its goal, and malaria is currently endemic in 101 member countries consisting of 45 countries in the African region, 21 in the Americas, 4 in the European region, 14 in the Eastern Mediterranean region, 8 in the Southeast Asian region, and 9 in the Western Pacific region. Malaria is a puzzle because even after 30 years of experimentation, researchers are still looking for a vaccine. Although several vaccines (e.g., multi-gene DNA vaccine, protein vaccine, and synthetic peptide vaccine) using the latest technology are presently being developed, scientists conclude that it could take 7-15 years before an effective vaccine is made available. Furthermore, as malaria continues to infect 300 million people and to kill over 1 million per year, a challenge is seen in the inadequate health care services and impoverished socioeconomic conditions of the underdeveloped areas where this disease is most evident. Early diagnosis, immediate treatment, and preventive measures are identified as the key priorities in malaria control in the meantime. In addition, the ancient treatments such as artemisinin and quinine are also considered effective.
疟疾:失败、困惑、挑战。
疟疾是20世纪最复杂的健康问题之一,据说与疟疾的斗争是失败的,是一个难题,也是一个挑战。这场斗争是失败的,因为1956年开始的世界卫生组织全球根除计划从未实现其目标,目前疟疾在101个成员国中流行,其中包括非洲地区的45个国家,美洲地区的21个国家,欧洲地区的4个国家,东地中海地区的14个国家,东南亚地区的8个国家和西太平洋地区的9个国家。疟疾是一个谜,因为即使经过30年的实验,研究人员仍在寻找疫苗。虽然目前正在开发几种使用最新技术的疫苗(例如,多基因DNA疫苗、蛋白质疫苗和合成肽疫苗),但科学家们认为,可能需要7-15年才能生产出有效的疫苗。此外,由于疟疾每年继续感染3亿人,造成100多万人死亡,在这种疾病最明显的不发达地区,保健服务不足和社会经济条件贫困是一项挑战。与此同时,早期诊断、立即治疗和预防措施被确定为疟疾控制的关键优先事项。此外,古老的治疗方法如青蒿素和奎宁也被认为是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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