{"title":"Responsive microgels and microgel assemblies in biocatalytic applications","authors":"Nidhi C. Dubey, Divya Gaur, Bijay P. Tripathi","doi":"10.1002/pol.20230031","DOIUrl":null,"url":null,"abstract":"<p>Microgels are soft particles that offer excellent colloidal stability, large surface area, and fluid-like transport characteristics, making them ideal for enzyme immobilization and reaction regulation. In recent years, the use of microgels in enzyme processes has rapidly increased and reviewed. Here in this review, we have provided a comprehensive overview of the strategies involved in microgel synthesis, practical aspects of microgel–enzyme conjugate formation, and the effects of microgel on enzyme stabilization and activities. In the end, we have discussed important biocatalytic applications of microgel and enzyme. The aim of this review is to provide a detailed understanding of enzyme–microgel conjugates and their potential applications, which can aid in the design of new microgels, responsive platforms, and biochemical applications.</p>","PeriodicalId":199,"journal":{"name":"Journal of Polymer Science Part A: Polymer Chemistry","volume":"61 16","pages":"1730-1748"},"PeriodicalIF":2.7020,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/pol.20230031","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Polymer Science Part A: Polymer Chemistry","FirstCategoryId":"1","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pol.20230031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Materials Science","Score":null,"Total":0}
引用次数: 3
Abstract
Microgels are soft particles that offer excellent colloidal stability, large surface area, and fluid-like transport characteristics, making them ideal for enzyme immobilization and reaction regulation. In recent years, the use of microgels in enzyme processes has rapidly increased and reviewed. Here in this review, we have provided a comprehensive overview of the strategies involved in microgel synthesis, practical aspects of microgel–enzyme conjugate formation, and the effects of microgel on enzyme stabilization and activities. In the end, we have discussed important biocatalytic applications of microgel and enzyme. The aim of this review is to provide a detailed understanding of enzyme–microgel conjugates and their potential applications, which can aid in the design of new microgels, responsive platforms, and biochemical applications.
期刊介绍：
Part A: Polymer Chemistry is devoted to studies in fundamental organic polymer chemistry and physical organic chemistry. This includes all related topics (such as organic, bioorganic, bioinorganic and biological chemistry of monomers, polymers, oligomers and model compounds, inorganic and organometallic chemistry for catalysts, mechanistic studies, supramolecular chemistry aspects relevant to polymer...
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