{"title":"Echinacea for the prevention and treatment of upper respiratory infections","authors":"Adriane Fugh-Berman","doi":"10.1016/S1543-1150(03)00012-7","DOIUrl":null,"url":null,"abstract":"<div><p><span>Echinacea<span> products are widely used to treat and prevent colds and other infections. Three randomized, placebo-controlled trials found no benefit of echinacea-only products in preventing upper respiratory infections (URIs). However, six of seven randomized, placebo-controlled trials did a benefit for several </span></span>extracts echinacea<span><span> in treating URIs— E. pallida root, E. purpurea root, and E. purpurea pressed juice (NOTE: trials of E. purpurea root found no effect). Echinacea extracts contain alkylamides<span>, caffeic acid derivatives, ketoalkenes/ketoalkynes </span></span>glycoproteins<span>, and polysaccharides<span>; it is unknown which compounds are most active. Echinacea products have been associated with allergic skin reactions, asthma, urticaria/angioedema, and anaphylaxis.</span></span></span></p></div>","PeriodicalId":101156,"journal":{"name":"Seminars in Integrative Medicine","volume":"1 2","pages":"Pages 106-111"},"PeriodicalIF":0.0000,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1543-1150(03)00012-7","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in Integrative Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1543115003000127","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 12
Abstract
Echinacea products are widely used to treat and prevent colds and other infections. Three randomized, placebo-controlled trials found no benefit of echinacea-only products in preventing upper respiratory infections (URIs). However, six of seven randomized, placebo-controlled trials did a benefit for several extracts echinacea in treating URIs— E. pallida root, E. purpurea root, and E. purpurea pressed juice (NOTE: trials of E. purpurea root found no effect). Echinacea extracts contain alkylamides, caffeic acid derivatives, ketoalkenes/ketoalkynes glycoproteins, and polysaccharides; it is unknown which compounds are most active. Echinacea products have been associated with allergic skin reactions, asthma, urticaria/angioedema, and anaphylaxis.
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