A simple valid tool for measuring obesity-related-CHD risk in Sri Lankan adults

Carukshi Arambepola , Dulitha Fernando , Ruvan Ekanayake
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引用次数: 7

Abstract

Background

The significance of anthropometric measures of obesity that determine coronary-heart-disease (CHD) risk varies among populations. This study compares waist circumference (WC) and body mass index (BMI) in identifying the “obesity-related-CHD risk” among Sri Lankan adults.

Methods

A population-based cross-section of 515 adults aged 20–64 years, residing in the district of Colombo in 2004 was selected by a multi-stage, stratified, probability sampling method. WC, height and weight were measured. Demographic, socio-economic and lifestyle characteristics, smoking and obesity-related-CHD risk factors (hypertension, dyslipidaemia, diabetes) were assessed by questionnaires, physical measurements and biochemical assessments. “Obesity-related CHD risk” was defined by the presence of ⩾1 obesity-related-CHD risk factors.

Results

Compared to BMI, WC was a stronger correlate of systolic and diastolic blood pressure, triglycerides among both sexes and of plasma glucose among males. It was also an independent predictor of obesity-related-CHD risk in both males (beta co-efficient = 0.046; standard error = 0.013) and females (0.024; 0.012) in contrast to BMI, which was significant only among males (0.138; 0.037) in the logistic regression models adjusted for confounders. At the same level of obesity-related-CHD risk corresponding with BMI of 25 kg/m2 (OR = 1.7) and 30 kg/m2 (OR = 3.5), the corresponding WC values were 90.5 cm and 105.5 cm for males and 100 cm and 129 cm for females. The derived optimal risk thresholds of WC for identifying obesity-related-CHD risk was 88.5 cm for males and 82 cm for females.

Conclusions

WC with its sex-specific cutoff values can serve as a better screening tool than BMI in identifying individuals at risk of obesity-related CHD in low-resource settings.

测量斯里兰卡成年人肥胖相关冠心病风险的简单有效工具
背景:肥胖的人体测量测量在确定冠心病(CHD)风险方面的意义因人群而异。本研究比较了斯里兰卡成年人的腰围(WC)和身体质量指数(BMI),以确定“肥胖相关的冠心病风险”。方法采用多阶段、分层、概率抽样的方法,选取2004年居住在科伦坡地区的515名年龄在20 ~ 64岁的成年人作为调查对象。测量腰围、身高、体重。通过问卷调查、物理测量和生化评估评估人口统计学、社会经济和生活方式特征、吸烟和肥胖相关的冠心病危险因素(高血压、血脂异常、糖尿病)。“肥胖相关冠心病风险”是通过存在大于或等于1的肥胖相关冠心病风险因素来定义的。结果与BMI相比,WC与两性的收缩压和舒张压、甘油三酯和男性的血糖有更强的相关性。它也是两名男性肥胖相关冠心病风险的独立预测因子(β系数= 0.046;标准误差= 0.013),女性(0.024;0.012),仅在男性中显著(0.138;0.037)在调整混杂因素的逻辑回归模型中。在BMI为25 kg/m2 (OR = 1.7)和30 kg/m2 (OR = 3.5)的肥胖相关冠心病风险水平下,男性对应的WC值分别为90.5 cm和105.5 cm,女性对应的WC值分别为100 cm和129 cm。得出的识别肥胖相关冠心病风险的WC最佳风险阈值为男性88.5 cm,女性82 cm。结论在低资源环境下,swc具有性别特异性临界值,可作为比BMI更好的筛查工具,用于识别肥胖相关冠心病风险个体。
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