Monitorización de los efectos de la raquianestesia sobre la saturación de oxígeno cerebral en pacientes ancianos con el uso de espectroscopia de luz próxima al infrarrojo

Aysegul Kusku , Guray Demir , Zafer Cukurova , Gulay Eren , Oya Hergunsel
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Abstract

Objective

Central blockage provided by spinal anaesthesia enables realization of many surgical procedures, whereas hemodynamic and respiratory changes influence systemic oxygen delivery leading to the potential development of series of problems such as cerebral ischemia, myocardial infarction and acute renal failure. This study was intended to detect potentially adverse effects of hemodynamic and respiratory changes on systemic oxygen delivery using cerebral oxymetric methods in patients who underwent spinal anaesthesia.

Methods

Twenty-five ASA I–II Group patients aged 65–80 years scheduled for unilateral inguinal hernia repair under spinal anaesthesia were included in the study. Following standard monitorization baseline cerebral oxygen levels were measured using cerebral oximetric methods. Standardized Mini Mental Test (SMMT) was applied before and after the operation so as to determine the level of cognitive functioning of the cases. Using a standard technique and equal amounts of a local anaesthetic drug (15 mg bupivacaine 5%) intratechal blockade was performed. Mean blood pressure (MBP), maximum heart rate (MHR), peripheral oxygen saturation (SpO2) and cerebral oxygen levels (rSO2) were preoperatively monitored for 60 min. Pre- and postoperative haemoglobin levels were measured. The variations in data obtained and their correlations with the cerebral oxygen levels were investigated.

Results

Significant changes in pre- and postoperative measurements of haemoglobin levels and SMMT scores and intraoperative SpO2 levels were not observed. However, significant variations were observed in intraoperative MBP, MHR and rSO2 levels. Besides, a correlation between variations in rSO2, MBP and MHR was determined.

Conclusion

Evaluation of the data obtained in the study demonstrated that post-spinal decline in blood pressure and also heart rate decreases systemic oxygen delivery and adversely effects cerebral oxygen levels. However, this downward change did not result in deterioration of cognitive functioning.

利用近红外光谱学监测脊髓麻醉对老年患者脑氧饱和度的影响
目的脊髓麻醉造成的中枢阻滞使许多外科手术得以实现,而血流动力学和呼吸系统的改变影响全身氧输送,导致脑缺血、心肌梗死和急性肾功能衰竭等一系列问题的潜在发展。本研究旨在通过脑氧测量法检测脊髓麻醉患者血液动力学和呼吸变化对全身氧输送的潜在不良影响。方法选择ASA I-II组患者25例,年龄65 ~ 80岁,行单侧腹股沟疝脊髓麻醉修补术。在标准监测后,使用脑氧测定法测量基线脑氧水平。术前、术后分别采用标准化迷你心理测验(SMMT)测定患者的认知功能水平。使用标准技术和等量的局部麻醉药物(15 mg布比卡因5%)进行管内阻断。术前监测平均血压(MBP)、最大心率(MHR)、外周血氧饱和度(SpO2)和脑氧水平(rSO2) 60分钟。测定术前和术后血红蛋白水平。研究了所获得数据的变化及其与脑氧水平的相关性。结果术前和术后血红蛋白水平、SMMT评分和术中SpO2水平无明显变化。然而,术中MBP、MHR和rSO2水平存在显著差异。此外,还确定了rSO2、MBP和MHR的变化之间的相关性。结论:对研究数据的评估表明,脊柱后血压和心率的下降降低了全身氧输送,并对脑氧水平产生不利影响。然而,这种向下的变化并没有导致认知功能的恶化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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