Tratamento endovascular de doença arterial obstrutiva abaixo do joelho: existem limites para a revascularização? – experiência de 5 anos de um centro

Ricardo Gouveia , Pedro Brandão , Miguel Lobo , Daniel Brandão , João Vasconcelos , Pedro Sousa , Jacinta Campos , Andreia Coelho , Rita Augusto , Fernando Marinho , Alexandra Canedo
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引用次数: 0

Abstract

Introduction

Endovascular surgery is an effective way to treat below the knee disease in critical limb ischemia patients. It has been described to have high limb salvage rates with low associated morbidity and mortality. The purpose of this work is to review our results in below the knee endovascular procedures, focusing on complex below the knee lesions, particularly when it is uncertain if and which below the ankle and foot arteries are patent.

Material and methods

We did a retrospective analysis of our Department's experience in endovascular treatment of below the knee disease, including patients submitted to first procedures for a de novo critical limb ischemia, during the period from January/2010 to August/2014 (275 patients). We reviewed both clinical files and patients angiograms. The primary outcomes were: technical success rate, reintervention rate, limb salvage rate and lesion healing time. We did a subanalysis of the outcomes related to the treatment of long below the knee occlusions.

Results

Technical success in treating below the knee stenosis was 98.9%. Below the knee occlusions were detected in 54.9% of the patients (39.4% with at least one vessel with a long occlusion). Antegrade recanalization was attempted in all patients and achieved in 92.8%. Distal retrograde recanalization was successful in another 5.4% of the patients. In 23.6% of the patients a long occlusion recanalization was performed (27.6% of these patients had no aparent foot outflow before the recanalization). Failure rate was 3.6%. Reintervention rate was 26.2%. Limb salvage rate was 91.3% (one‐year). The mean time for ulcer healing was 5.3 months. More tibial vessels patent at the end of the procedure was associated with higher limb salvage rate (p = 0.026) and faster ulcer healing time (p = 0.015). For these parameters the angiossomic revascularization had a tendency to be associated with better results (p = 0.090 and 0.097 accordingly).

Conclusion

Hence we present favourable results in the endovascular treatment of below the knee disease, comparable to specialized centres. The treatment of long below the knee occlusions can be achieved, even when there is doubt of below the ankle arteries patency, thus presenting good short and medium term results.

膝关节以下阻塞性动脉疾病的血管内治疗:血管重建术有限制吗?- 5年中心工作经验
血管内手术是治疗危重肢体缺血患者膝下病变的有效方法。有报道称其残肢保留率高,相关发病率和死亡率低。这项工作的目的是回顾我们在膝关节以下血管内手术的结果,重点是复杂的膝关节以下病变,特别是当不确定踝关节和足部动脉是否通畅以及哪些通畅时。材料与方法回顾性分析2010年1月至2014年8月期间我科血管内治疗膝下病变的经验,包括首次手术治疗新生危重肢体缺血的患者(275例)。我们查阅了临床档案和患者血管造影。主要观察指标为:手术成功率、再干预率、残肢保留率和损伤愈合时间。我们做了一个与治疗膝以下长闭塞相关的结果的亚分析。结果治疗膝下狭窄的技术成功率为98.9%。54.9%的患者膝下有闭塞(39.4%至少有一条血管有长闭塞)。所有患者均尝试顺行再通,成功率为92.8%。另外5.4%的患者远端逆行再通成功。23.6%的患者进行了长闭塞再通(27.6%的患者在再通之前没有明显的足部流出)。失败率为3.6%。再干预率为26.2%。肢体保留率为91.3%(1年)。溃疡愈合平均时间为5.3个月。手术结束时更多的胫骨血管通畅与更高的肢体保留率(p = 0.026)和更快的溃疡愈合时间(p = 0.015)相关。对于这些参数,血管再生有较好的结果(p = 0.090和0.097)。结论:我们在血管内治疗膝关节以下疾病方面取得了与专业中心相当的良好效果。即使在怀疑踝关节以下动脉是否通畅的情况下,也可以治疗长膝以下闭塞,从而获得良好的中短期效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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