Correlation between bladder compliance and the content of detrusor collagen fibers

Frontiers of Nursing Pub Date : 2016-06-01 DOI:10.1016/j.cnre.2016.01.003

Hai-Yan Zhang , Hai-Xu Ji , Wei Li , Jin-Hua Zhang

{"title":"Correlation between bladder compliance and the content of detrusor collagen fibers","authors":"Hai-Yan Zhang , Hai-Xu Ji , Wei Li , Jin-Hua Zhang","doi":"10.1016/j.cnre.2016.01.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To explore the possible correlation between bladder compliance (BC) and the changes in detrusor collagen fiber content after bladder outlet obstruction (BOO).</p></div><div><h3>Methods</h3><p>Ninety healthy female Sprague-Dawley (SD) rats were enrolled in this experiment and divided into an experimental group and a control group randomly, using the randomizing table method, with 70 rats in the experimental group and 20 rats in the control group. Six weeks after BOO modeling was established, BC was evaluated through bladder testing. Bladder tissues were then fixed and embedded in paraffin. The tissues were cut into thin slices, followed by Masson staining and observation under a microscope.</p></div><div><h3>Results</h3><p>Compared with the control group, the BC of the experimental group rats increased, and the difference had statistical significance (<em>P</em> < 0.05); the content of detrusor collagen fibers of the rats in the experimental group increased significantly compared to the control group.</p></div><div><h3>Conclusions</h3><p>The content of detrusor collagen fibers increased significantly after BOO, and BC was higher.</p></div>","PeriodicalId":57172,"journal":{"name":"Frontiers of Nursing","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cnre.2016.01.003","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers of Nursing","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2095771816300512","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 3

Abstract

Objective

To explore the possible correlation between bladder compliance (BC) and the changes in detrusor collagen fiber content after bladder outlet obstruction (BOO).

Methods

Ninety healthy female Sprague-Dawley (SD) rats were enrolled in this experiment and divided into an experimental group and a control group randomly, using the randomizing table method, with 70 rats in the experimental group and 20 rats in the control group. Six weeks after BOO modeling was established, BC was evaluated through bladder testing. Bladder tissues were then fixed and embedded in paraffin. The tissues were cut into thin slices, followed by Masson staining and observation under a microscope.

Results

Compared with the control group, the BC of the experimental group rats increased, and the difference had statistical significance (P < 0.05); the content of detrusor collagen fibers of the rats in the experimental group increased significantly compared to the control group.

Conclusions

The content of detrusor collagen fibers increased significantly after BOO, and BC was higher.

查看原文本刊更多论文

膀胱顺应性与逼尿肌胶原纤维含量的关系

目的探讨膀胱出口梗阻(BOO)后膀胱顺应性(BC)与逼尿肌胶原纤维含量变化的关系。方法选用健康雌性SD大鼠90只，采用随机表法随机分为实验组和对照组，实验组70只，对照组20只。BOO模型建立6周后，通过膀胱检查评估BC。然后将膀胱组织固定并包埋于石蜡中。将组织切成薄片，进行马松染色，显微镜下观察。结果与对照组比较，实验组大鼠BC升高，差异有统计学意义(P <0.05);实验组大鼠逼尿肌胶原纤维含量较对照组明显增加。结论BOO术后逼尿肌胶原纤维含量明显增高，BC增高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Frontiers of Nursing

自引率

0.00%

发文量

353