{"title":"Toxicity, metabolism and distribution of lindane in lepidopterous larvae","authors":"N.A. Khan","doi":"10.1016/0742-8413(93)90057-R","DOIUrl":null,"url":null,"abstract":"<div><p>1. Lindane was generally more toxic when ingested than when applied topically to similar sized larvae of <em>Mamestra brassicae</em> (L) (4th-instar), <em>Spodoptera littoralis</em> (Boisd) (4th-instar), <em>Pieris brassicae</em> (L) (3rd-instar), and <em>Bombyx mori</em> (L) (2nd-instar).</p><p>2. <em>In vivo</em> metabolism of ingested <sup>14</sup>C-lindane decreased in order of <em>S. littoralis > P. brassicae > B. mori</em> (based on the recovery of metabolised <sup>14</sup>C-lindane form the larva and frass) and followed the order of increasing susceptibility.</p><p>3. <sup>14</sup>C-lindane was regurgitated after ingestion; its effects on insecticidal action are discussed.</p><p>4. The causes of variation in interspecies susceptibility with particular reference to concepts of resistance as influenced by polyphagy versus monophagy are discussed.</p></div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"105 1","pages":"Pages 55-61"},"PeriodicalIF":0.0000,"publicationDate":"1993-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90057-R","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comparative biochemistry and physiology. C: Comparative pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/074284139390057R","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
1. Lindane was generally more toxic when ingested than when applied topically to similar sized larvae of Mamestra brassicae (L) (4th-instar), Spodoptera littoralis (Boisd) (4th-instar), Pieris brassicae (L) (3rd-instar), and Bombyx mori (L) (2nd-instar).
2. In vivo metabolism of ingested 14C-lindane decreased in order of S. littoralis > P. brassicae > B. mori (based on the recovery of metabolised 14C-lindane form the larva and frass) and followed the order of increasing susceptibility.
3. 14C-lindane was regurgitated after ingestion; its effects on insecticidal action are discussed.
4. The causes of variation in interspecies susceptibility with particular reference to concepts of resistance as influenced by polyphagy versus monophagy are discussed.
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