Diabetic ketoacidosis following steroid treatment in a patient with gestational diabetes mellitus

L. Alexandre, K. Shipman, A. Brahma, J. Turner, T. Wallace, K. Stanley, R. Temple
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引用次数: 3

Abstract

In addition, metabolic changes inpregnancy increase the risk of DKA.These include insulin resistancecaused by increased circulating levels of hormones including prog-esterone, oestrogen, cortisol andhuman placental lactogen in thecontext of reduced buffering capacity due to decreased bloodbicarbonate levels secondary to res-piratory alkalosis in pregnancy.
妊娠期糖尿病患者类固醇治疗后糖尿病酮症酸中毒1例
此外,妊娠期的代谢变化也会增加患DKA的风险。其中包括胰岛素抵抗,这是由于妊娠期呼吸性碱中毒引起的血液碳酸氢盐水平降低,导致循环激素水平增加,包括孕激素、雌激素、皮质醇和人胎盘乳酸,从而导致缓冲能力降低。
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