Transmission Dynamics of COVID-19 with Saturated Treatment: A Case Study of Spain

IF 1.5 4区 物理与天体物理 Q2 PHYSICS, MULTIDISCIPLINARY
Jayanta Kumar Ghosh, Pritam Saha, Md Kamrujjaman, Uttam Ghosh
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引用次数: 2

Abstract

In this paper, an epidemic compartmental model with saturated type treatment function is presented to investigate the transmission dynamics of COVID-19 with a case study of Spain (in Europe). We obtain the basic reproduction number of the model which plays a very important role in disease spreading. We show that if the basic reproduction number is less than unity then the disease-free equilibrium point is locally asymptotically stable, but making the basic reproduction number less than unity is not sufficient to eradicate COVID-19 infection which is shown through backward bifurcation. The model is validated with the real COVID-19 data of Spain (in Europe), Algeria (in Africa), and India (in Asia) and also estimated important model parameters in all cases. The effect of an important model parameter for controlling the disease spreading is also investigated for the infection scenario of Spain only. We establish that the asymptomatic class plays a very important role for spreading this pandemic disease. The effective reproduction number has been estimated which varies in time in Spain. Finally, the model is reformulated as an optimal control problem which shows that the social distancing due to adapting a partial lockdown by some countries is highly effective for controlling COVID-19.

饱和处理下新冠肺炎传播动态——以西班牙为例
本文以西班牙(欧洲)为例,建立了具有饱和型处理函数的流行病区室模型,研究了COVID-19的传播动力学。我们得到了在疾病传播中起重要作用的模型的基本繁殖数。我们证明了如果基本繁殖数小于单位,则无病平衡点是局部渐近稳定的,但使基本繁殖数小于单位不足以根除COVID-19感染,这是通过后向分岔证明的。用西班牙(欧洲)、阿尔及利亚(非洲)和印度(亚洲)的真实COVID-19数据对模型进行了验证,并在所有情况下估计了重要的模型参数。对控制疾病传播的一个重要模型参数的影响也仅针对西班牙的感染情况进行了调查。由此可见,无症状人群在疫情传播中起着非常重要的作用。在西班牙,有效繁殖数随时间的变化而变化。最后,将模型重新表述为一个最优控制问题,该问题表明,由于适应部分国家的部分封锁而产生的社会距离对控制COVID-19非常有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Brazilian Journal of Physics
Brazilian Journal of Physics 物理-物理:综合
CiteScore
2.50
自引率
6.20%
发文量
189
审稿时长
6.0 months
期刊介绍: The Brazilian Journal of Physics is a peer-reviewed international journal published by the Brazilian Physical Society (SBF). The journal publishes new and original research results from all areas of physics, obtained in Brazil and from anywhere else in the world. Contents include theoretical, practical and experimental papers as well as high-quality review papers. Submissions should follow the generally accepted structure for journal articles with basic elements: title, abstract, introduction, results, conclusions, and references.
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