Transcatheter closure of ventricular septal defects

Yongwen Qin
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引用次数: 28

Abstract

Objective: To evaluate the feasibility and effect of transcatheter closure of ventricular septal defects(VSD) using the VSD occluder.Methods: From December 2003 to March 2005,13 VSD patients,8 males and 5 females,ranging in age from 4 to 35(15.2±10.7)years,underwent catheter closure using the VSD occluder.Tthe mean diameter of the VSD obtained by transthoracic echocardiography was 4-12(5.4±1.2) mm.Transcatheter closure was performed under transthoracic echocardiographic guidance after left ventriculography.All patients were followed up 1,3 and 6 months after the procedures. Results: The devices were successfully placed in 12 of the patients and complete closure achieved in 11.Trace residual shunt was observed in 1 patient but disappeared within 10 minutes.No severe complications were noted except 1 case of complete right bundle branch block revealed by electrocardiography. Conclusion: Transcatheter closure of VSD by the VSD occluder is a safe and effective procedure,with good immediate results.Further clinical trials are under way to assess its long-term effect.
经导管闭合室间隔缺损
目的:探讨应用室间隔缺损封堵器经导管治疗室间隔缺损的可行性及效果。方法:2003年12月至2005年3月,对13例VSD患者行VSD闭锁术,男8例,女5例,年龄4 ~ 35岁(15.2±10.7)岁。经胸超声心动图示VSD平均直径为4-12(5.4±1.2)mm,左心室造影后在经胸超声心动图引导下关闭导管。术后随访1、3、6个月。结果:12例患者成功放置器械,11例患者完全闭合。1例患者观察到微量残留分流,但在10分钟内消失。除1例心电图示完全性右束支阻滞外,未见严重并发症。结论:经导管VSD封堵器封闭VSD是一种安全、有效的手术方法,立时效果良好。进一步的临床试验正在进行中,以评估其长期效果。
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