A Comprehensive Review on the Classification, Uses, Sources of Nanoparticles (NPs) and Their Toxicity on Health

IF 1.6 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES
Laxmi Kant Bhardwaj, Prangya Rath, Moharana Choudhury
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引用次数: 2

Abstract

Nanotechnology (NT) refers to the generation and application of nanoparticles (NPs). Research in NT has been ongoing for several decades and has resulted in a wide range of materials at the nano-scale. Globally, NPs serve various domestic, pharmaceuticals, aviation, textiles, and other industrial purposes. These particles are currently used in kitchen utensils, medical applications, energy-related research, aircraft, etc. The future of our planet depends on NT. Numerous molecular indicators of genetic and autoimmune diseases, malignant tumors, and a wide range of other disorders can currently be diagnosed using NPs. Drug delivery to specific tissues and organs with controlled drug release and accumulation parameters is achieved through NPs. In addition, NPs have been used as active components in some cases. For example, photodynamic therapy’s incorporation and heating are photosensitizers and hyper-thermic tumor killing through NPs. Despite numerous beneficiary use and economic success of NPs, their toxic effects on terrestrial and aquatic ecosystems have also gained attention. Excessive exposure to NPs in sectors, such as agriculture, industry, etc. has generated negative health effects in humans. The review highlights about NPs in great detail. The paper discusses their sources, usage, toxicity and health effects, transportation, analysis, and treatment. It represents a summary of recent research developments and achievements in the field of NT and substantial gap areas that need to be addressed.

纳米颗粒的分类、用途、来源及其健康毒性综述
纳米技术是指纳米颗粒的产生和应用。NT的研究已经进行了几十年,并产生了广泛的纳米级材料。在全球范围内,NP服务于各种国内、制药、航空、纺织和其他工业用途。这些颗粒目前用于厨房用具、医疗应用、能源相关研究、飞机等。我们星球的未来取决于NT。目前可以使用NP诊断遗传和自身免疫性疾病、恶性肿瘤和各种其他疾病的许多分子指标。通过NP实现药物向特定组织和器官的递送,并控制药物释放和积聚参数。此外,在某些情况下,NP已被用作活性成分。例如,光动力疗法的掺入和加热是光敏剂和通过NP的高温肿瘤杀伤。尽管NPs的许多受益者使用和经济成功,但其对陆地和水生生态系统的毒性影响也引起了关注。在农业、工业等部门过度接触NPs对人类健康产生了负面影响。该评论非常详细地强调了NPs。本文讨论了它们的来源、用途、毒性和健康影响、运输、分析和治疗。它总结了NT领域的最新研究进展和成就,以及需要解决的重大差距领域。
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来源期刊
Aerosol Science and Engineering
Aerosol Science and Engineering Environmental Science-Pollution
CiteScore
3.00
自引率
7.10%
发文量
42
期刊介绍: ASE is an international journal that publishes high-quality papers, communications, and discussion that advance aerosol science and engineering. Acceptable article forms include original research papers, review articles, letters, commentaries, news and views, research highlights, editorials, correspondence, and new-direction columns. ASE emphasizes the application of aerosol technology to both environmental and technical issues, and it provides a platform not only for basic research but also for industrial interests. We encourage scientists and researchers to submit papers that will advance our knowledge of aerosols and highlight new approaches for aerosol studies and new technologies for pollution control. ASE promotes cutting-edge studies of aerosol science and state-of-art instrumentation, but it is not limited to academic topics and instead aims to bridge the gap between basic science and industrial applications.  ASE accepts papers covering a broad range of aerosol-related topics, including aerosol physical and chemical properties, composition, formation, transport and deposition, numerical simulation of air pollution incidents, chemical processes in the atmosphere, aerosol control technologies and industrial applications. In addition, ASE welcomes papers involving new and advanced methods and technologies that focus on aerosol pollution, sampling and analysis, including the invention and development of instrumentation, nanoparticle formation, nano technology, indoor and outdoor air quality monitoring, air pollution control, and air pollution remediation and feasibility assessments.
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