A 5-year follow-up of a female patient with Kleine-Levin syndrome: Diagnosis,disease course and management

Rare Pub Date : 2023-01-01 DOI:10.1016/j.rare.2023.100003
Prabhoo Dayal, Virendra Vikram Singh, Ravikant Kumar
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Abstract

Kleine-Levin syndrome (KLS) is a rare illness of recurrent episodes of hypersomnia associated with hyperphagia, cognitive dysfunctions and behavioural abnormalities. KLS, a disorder often reported in young males has been described in fewer females. It is rare in patients with age beyond second decade. We report a case of a female in early thirties who presented with recurrent episodes of excessive sleepiness and hyperphagia with cognitive dysfunctions. Her eating and subsequent weight gain was so prominent that she was referred to addiction treatment centre. She was managed with Lithium and Modafinil.

1例Kleine-Levin综合征女性患者5年随访:诊断、病程及治疗
Kleine-Levin综合征(KLS)是一种罕见的伴有高进食、认知功能障碍和行为异常的嗜睡复发性疾病。KLS,一种常见于年轻男性的疾病,在较少的女性中被描述。这在年龄超过第二个十岁的患者中是罕见的。我们报告了一例30岁出头的女性,她反复出现过度嗜睡和进食过多,并伴有认知功能障碍。她的饮食和随后的体重增加非常突出,以至于她被转诊到戒毒中心。她接受了锂和莫达非尼的治疗。
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