A novel apparatus to assess intraoperative intrarenal pelvic pressure and associated clinical outcomes

Alex J. Xu , Kirtishri Mishra , Nabeel Shakir , Lee Cheng Zhao
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Abstract

Objective

To design a simple, novel, economical apparatus which effectively provides reliable, real-time measurements of intrarenal pelvic pressure (IRPP) intraoperatively and to demonstrate clinical utility.

Patients and Surgical Procedure

Patients undergoing robotic ureteral reconstruction from 10/2020 to 7/2021 for whom intraoperative IRPP measurement was conducted were included.

Baseline opening pressure was noted with the pelvis completely drained. The kidney was intermittently drained when IRPP exceeded a certain threshold, returning the pressure to baseline. Relief of obstruction was defined as return of IRPP to physiologic value without further increases for the remainder of surgery.

Demographic, intraoperative, and post-operative variables were collected and IRPP measurements extracted. Post-operative success was defined as resolution of obstruction by clinical symptoms and imaging.

Results

Eleven patients met criteria including 4 (36.4%) men and 7 (63.6%) women. Median age and BMI was 61 years (range 14–23) and 26 kg/m2 (range 17.2–42), respectively. Six patients (54.5%) had undergone prior interventions.

Ureteral reconstructive procedures included bilateral refluxing reimplants (2), unilateral reimplant with Boari flap (3), non-transecting reimplant (2), unilateral ileal ureter (1), bilateral ileal ureter (1), buccal ureteroplasty (1), and ureteroureterostomy (1). Median peak IRPP was 52 mmHg (range 27–59) and median nadir IRPP was 14 mmHg (range 1–24), with median decrease of 36 mmHg (range 26–84).

At median follow-up of 120 days, all patients had successful repairs.

Conclusions

Intraoperative measurement of IRPP can be utilized in patients with percutaneous nephrostomy tubes using readily available equipment. This measurement has the potential to ensure that ureteral obstruction is completely relieved and to prevent development of supraphysiologic IRPP during surgery.

一种评估术中肾内盆腔压力及相关临床结果的新型仪器
目的设计一种简单、新颖、经济的仪器,有效地在术中提供可靠、实时的肾盂内压(IRPP)测量,并证明其临床实用性。患者和手术程序包括2020年10月至2021年7月接受机器人输尿管重建的患者,他们在术中进行了IRPP测量。在骨盆完全排水的情况下,观察到基线开放压力。当IRPP超过一定阈值时,肾脏间歇性排水,使压力恢复到基线。梗阻的缓解被定义为IRPP恢复到生理值,而在剩余的手术中没有进一步增加。收集人口统计学、术中和术后变量,并提取IRPP测量值。术后成功的定义是通过临床症状和影像学来解决梗阻。结果11例患者符合标准,其中男性4例(36.4%),女性7例(63.6%)。中位年龄和BMI分别为61岁(范围14-23)和26 kg/m2(范围17.2-42)。6名患者(54.5%)曾接受过干预。输尿管重建手术包括双侧回流再植入术(2)、单侧Boari皮瓣再植入术3、非横断再植入术2、单侧回肠输尿管(1)、双侧回肠输尿管(一)、颊侧输尿管成形术1和输尿管造瘘术1。中位峰值IRPP为52毫米汞柱(范围27-59),中位最低点IRPP为14毫米汞柱,中位下降36毫米汞柱。中位随访120天时,所有患者均获得成功修复。结论IRPP的中期测量可用于经皮肾造瘘管患者使用现成的设备。这种测量有可能确保输尿管梗阻完全缓解,并防止手术过程中出现超生理性IRPP。
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来源期刊
Urology video journal
Urology video journal Nephrology, Urology
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