Effectiveness of oral bromelain on third molar surgery patients: A systematic review of systematic reviews

Advances in Oral and Maxillofacial Surgery Pub Date : 2023-09-09 DOI:10.1016/j.adoms.2023.100449

Feras AlMofreh AlQahtani , Sam Kuriadom , Mohammed S. AlSaleh , Hamedy AlAnzy , Jeny Mary George , Nouf AlShahri

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Abstract

Purpose

This review aimed to evaluate the current evidence on the effectiveness of bromelain in controlling postoperative pain, swelling, and trismus associated with third the molar surgery.

Results

The search strategy produced 26 articles. After reading the abstracts, 8 articles were excluded and the full-text articles in English of the remaining 18 studies were separately examined for eligibility by 2 authors, with 12 studies being excluded because they did not fit the inclusion criteria. Finally, 6 systematic reviews satisfied the criteria for inclusion and were processed for critical evaluation, with all the included studies reporting high quality evidence according to the Grading of Recommendations, Assessment, Development, and Evaluation system.

Conclusions

Oral Bromelain has been shown to reduce postoperative pain, improve a patient's quality of life and reduce the need for postoperative analgesics after third molar surgery. However, oral bromelain have no effect in reducing postoperative trismus and oedema.

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口服菠萝蛋白酶对第三磨牙手术患者的疗效:系统综述的系统综述

目的本综述旨在评估菠萝蛋白酶在控制第三磨牙手术后疼痛、肿胀和牙痛方面的有效性。结果检索策略共产生26篇文章。在阅读摘要后，8篇文章被排除在外，其余18项研究的英文全文文章由2名作者分别检查其资格，其中12项研究因不符合纳入标准而被排除在内。最后，6项系统审查符合纳入标准，并进行了批判性评估，所有纳入的研究都根据建议、评估、发展和评估系统的分级报告了高质量的证据。结论口腔菠萝蛋白酶已被证明可以减轻第三磨牙手术后的术后疼痛，提高患者的生活质量，并减少对术后镇痛药的需求。然而，口服菠萝蛋白酶对减少术后牙痛和水肿没有效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advances in Oral and Maxillofacial Surgery

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