{"title":"Malignant hyperthermia: A case report","authors":"Fereshteh Amiri, Mahbobeh Rashidi, Mohsen Savaei","doi":"10.1016/j.hpr.2023.300693","DOIUrl":null,"url":null,"abstract":"<div><p>Malignant hyperthermia is a rare hypermetabolic pharmacogenetic pathologic disorder of calcium release control in skeletal muscle following exposure to depolarizing muscle relaxants and inhalational anesthetics in general anesthesia. This report describes the case of a 32-year-old man undergoing emergency laparotomy after being shot in the stomach. The patient suffered a malignant hyperthermia attack following the administration of Succinylcholine to induce anesthesia and Isoflurane to maintain anesthesia. Eventually, we were able to treat the patient for malignant hyperthermia successfully.</p></div>","PeriodicalId":100612,"journal":{"name":"Human Pathology Reports","volume":"31 ","pages":"Article 300693"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Pathology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772736X23000038","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Malignant hyperthermia is a rare hypermetabolic pharmacogenetic pathologic disorder of calcium release control in skeletal muscle following exposure to depolarizing muscle relaxants and inhalational anesthetics in general anesthesia. This report describes the case of a 32-year-old man undergoing emergency laparotomy after being shot in the stomach. The patient suffered a malignant hyperthermia attack following the administration of Succinylcholine to induce anesthesia and Isoflurane to maintain anesthesia. Eventually, we were able to treat the patient for malignant hyperthermia successfully.