Gastrointestinal Bleeding Caused by Large Intestine Amyloidosis.

Nikhil Seth, Victoria A Jaeger, Namisha Thapa, James T Sing, Christopher R Naumann
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引用次数: 0

Abstract

Background: Amyloidosis is a rare disorder caused by abnormal folding of proteins, leading to the dysfunction of normal tissues. Amyloid deposition can affect several organs, but deposition in the large intestine is rare.

Case presentation: A 79-year-old man presented with gastrointestinal bleeding and nonspecific symptoms of weight loss, dry heaves, dysphagia, and weakness. The patient underwent esophagogastroduodenoscopy and colonoscopy and a biopsy confirmed the diagnosis of intestinal amyloidosis.

Conclusions: This case report highlights the importance of a strong differential when working up gastrointestinal bleeding that includes amyloidosis. Early identification and multidisciplinary involvement are crucial for management and tailored care to each patient's needs.

大肠淀粉样变性引起的胃肠道出血。
背景:淀粉样变性是一种罕见的由蛋白质折叠异常引起的疾病,可导致正常组织功能障碍。淀粉样蛋白沉积可以影响几个器官,但在大肠中的沉积是罕见的。病例介绍:一名79岁的男性出现胃肠道出血和非特异性症状,如体重减轻、干呕、吞咽困难和虚弱。患者接受了食管胃十二指肠镜和结肠镜检查,活检证实了肠淀粉样变性的诊断。结论:本病例报告强调了在处理包括淀粉样变性在内的胃肠道出血时进行强鉴别的重要性。早期识别和多学科参与对于管理和根据每位患者的需求量身定制的护理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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