The assessment of immunological parameters (Anti- Thyroid peroxidase antibody and Anti-Thyroglobin antibody) in premenopausal thyroid women patients

Cardiometry Pub Date : 2023-03-01 DOI:10.18137/cardiometry.2023.26.242247

Z. S. Mahmod, H. Jaffat

引用次数: 0

Abstract

Background: Thyroid diseases may be complicated by anti-thyroglobin and anti-thyroid peroxidase antibodies. Objective: This research examined thyroid diseases and serum Anti-TPO Ab and Anti-Tg Ab levels. Methods: Al-Fadel foundation for training and development (research foundation) in Babylon province conducted this cross-sectional study. The research comprised 90 patients aged 15–45, separated into three groups: 60 patients with thyriodism, 30 healthy participants as a control group, and all patients (n=60) into two groups: hypothyroidism and hyperthyroidism. Results: Hyperthyroidism and hypothyroidism patients and healthy controls had similar mean Anti TPO levels. Compared to healthy controls, hypothyroidism and hyperthyroidism patient groups increased significantly. Hypothyroidism and hyperthyroidism patients had higher Anti Tg levels than the health control group. Conclusion: Anti-TOP Ab and Anti-Tg Ab vary significantly between Hyperthyroidism, Hypothyroidism, and control. Clinical labs should evaluate thyroidism patients for potential consequences using these biomarkers.

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绝经前甲状腺妇女免疫参数（抗甲状腺过氧化物酶抗体和抗甲状腺球蛋白抗体）的评估

背景：甲状腺疾病可能因抗甲状腺球蛋白和抗甲状腺过氧化物酶抗体而复杂化。目的：检测甲状腺疾病患者血清抗TPO-Ab和抗Tg-Ab水平。方法：Al Fadel培训与发展基金会（研究基金会）在巴比伦省进行了这项横断面研究。这项研究包括90名15-45岁的患者，分为三组：60名甲状腺功能亢进患者，30名健康参与者作为对照组，所有患者（n=60）分为两组：甲状腺功能减退症和甲状腺功能亢进症。结果：甲状腺功能亢进症和甲状腺功能减退症患者和健康对照组的平均抗TPO水平相似。与健康对照组相比，甲状腺功能减退症和甲状腺功能亢进症患者组显著增加。甲状腺功能减退和甲状腺功能亢进患者的抗Tg水平高于健康对照组。结论：甲状腺功能亢进症、甲状腺功能减退症和正常对照组的抗TOP抗体和抗Tg抗体差异显著。临床实验室应使用这些生物标志物评估甲状腺炎患者的潜在后果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiometry MEDICAL LABORATORY TECHNOLOGY-

自引率

0.00%

发文量

审稿时长

6 weeks

期刊介绍： Cardiometry is an open access biannual electronic journal founded in 2012. It refers to medicine, particularly to cardiology, as well as oncocardiology and allied science of biophysics and medical equipment engineering. We publish mainly high quality original articles, reports, case reports, reviews and lectures in the field of the theory of cardiovascular system functioning, principles of cardiometry, its diagnostic methods, cardiovascular system therapy from the aspect of cardiometry, system and particular approaches to maintaining health, engineering peculiarities in cardiometry developing. The interdisciplinary areas of the journal are: hemodynamics, biophysics, biochemistry, metrology. The target audience of our Journal covers healthcare providers including cardiologists and general practitioners, bioengineers, biophysics, medical equipment, especially cardiology diagnostics device, developers, educators, nurses, healthcare decision-makers, people with cardiovascular diseases, cardiology and engineering universities and schools, state and private clinics. Cardiometry is aimed to provide a wide forum for exchange of information and public discussion on above scientific issues for the mentioned experts.