Application of virtual reality technology in the operation of brain tumors in central cortex and adjacent areas

Q4 Medicine

中华神经外科杂志 Pub Date : 2020-03-28 DOI:10.3760/CMA.J.CN112050-20190221-00059

Wei Gao, Yongfeng Bi, Ming Ye, Chaoqun Wu, Zhong Wang, Zhengquan Yu

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引用次数: 0

Abstract

Objective To address the value of multimodal image-based virtual reality technology in preoperative evaluation of resection of brain tumor in central cortex and adjacent areas. Methods A retrospective study was conducted on the clinical data of 36 patients with brain tumor in central cortex and adjacent areas who were admitted to Neurosurgery Department of the First Affiliated Hospital of Soochow University from December 2015 to April 2018. All patients underwent preoperative 3.0T MRI scan. Multimodal MRI images were then co-registered with the software iPlan followed by three-dimensional image reconstruction to generate virtual reality images. Evaluation of the relationship between tumor, brain vessels and eloquent areas was then performed according to the virtual reality model and compared with intra-operative findings. The brain tumors were resected under craniotomy microscope. Medical imaging examination and follow-up were performed after operation. Results For prediction of the relationship between tumor, eloquent area and vessels, multimodal image-based virtual reality showed the sensitivity of 94.4% (34/36). Among all 36 patients, total resection of glioma was achieved in 16 cases and subtotal resection in 2; total resection of meningioma was performed in 9 cases and subtotal resection in 1; total resection was achieved in 5 cases of cavernous hemangioma, 2 cases of metastatic tumor and 1 case of lymphoma. After surgery, 3 patients developed different degrees of limb motor impairment, of which 2 returned to normal after 3 months. One case developed transient speech disorders after surgery and returned to normal after 1 week. All patients were followed up for 20.2±5.4 months (10-38 months), and there were 3 patients showing recurrence in imaging examination. Conclusion The use of virtual reality technology is helpful to make an accurate assessment of the relationship between tumor and eloquent area as well as blood vessels near the tumor before surgery, and can help to improve the preoperative plan and improve the rate of total removal of tumor, thereby reducing the occurrence of postoperative complications. Key words: Brain neoplasms; Microsurgery; Eloquent area; Virtual reality; Multimodel

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虚拟现实技术在大脑中央皮层及邻近区域肿瘤手术中的应用

目的探讨基于多模式图像的虚拟现实技术在中央皮质及邻近区域脑肿瘤切除术前评估中的价值。方法对苏州大学附属第一医院神经外科2015年12月至2018年4月收治的36例中央皮质及邻近区域脑肿瘤患者的临床资料进行回顾性分析。所有患者均行术前3.0T MRI扫描。然后将多模式MRI图像与iPlan软件共同配准，然后进行三维图像重建以生成虚拟现实图像。然后根据虚拟现实模型评估肿瘤、脑血管和有说服力区域之间的关系，并与术中结果进行比较。在开颅显微镜下切除脑肿瘤。术后进行医学影像学检查和随访。结果基于多模式图像的虚拟现实对肿瘤、舌区和血管之间关系的预测灵敏度为94.4%（34/36）。36例患者中，胶质瘤全切除16例，次全切除2例；脑膜瘤全切除9例，次全切除1例；海绵状血管瘤5例，转移瘤2例，淋巴瘤1例，全部切除。术后，3名患者出现不同程度的肢体运动障碍，其中2名患者在3个月后恢复正常。1例患者在手术后出现短暂性言语障碍，1周后恢复正常。所有患者随访20.2±5.4个月（10-38个月），影像学检查有3例复发。结论虚拟现实技术的应用有助于术前准确评估肿瘤与肿瘤周围血管的关系，有助于完善术前计划，提高肿瘤全切除率，减少术后并发症的发生。关键词：脑肿瘤；显微外科；细长区域；虚拟现实；多模型

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来源期刊

中华神经外科杂志 Medicine-Surgery

CiteScore

0.10

自引率

0.00%

发文量

10706

期刊介绍： Chinese Journal of Neurosurgery is one of the series of journals organized by the Chinese Medical Association under the supervision of the China Association for Science and Technology. The journal is aimed at neurosurgeons and related researchers, and reports on the leading scientific research results and clinical experience in the field of neurosurgery, as well as the basic theoretical research closely related to neurosurgery.Chinese Journal of Neurosurgery has been included in many famous domestic search organizations, such as China Knowledge Resources Database, China Biomedical Journal Citation Database, Chinese Biomedical Journal Literature Database, China Science Citation Database, China Biomedical Literature Database, China Science and Technology Paper Citation Statistical Analysis Database, and China Science and Technology Journal Full Text Database, Wanfang Data Database of Medical Journals, etc.