Chronic Cavitary Pulmonary Aspergillosis: An Unusual Cause of Chronic Cough, Pleuritic Chest Pain, and Hemoptysis in a 24-Year-Old Coal Mine Worker

E. I. Sherfinski, E. Vore, M. Cooper, Peimei He
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Abstract

Pulmonary Aspergillus infections are caused by the ubiquitous fungus mold when spores found in compost, dust, and plant material are inhaled. Manifestation of the disease is represented by a delicate balance between host and pathogen interactions, making Aspergillus infection more commonly observed in immunocompromised individuals. Chronic cavitary pulmonary aspergillosis (CCPA) is a subtype of pulmonary Aspergillosis associated with a history of chronic or prior lung disease. Here, we present the case of a non-immunocompromised 24-year-old male with a history of intermittent asthma with chronic pulmonary symptoms and a finding of a lung mass on imaging. We describe the diagnostic challenge and surgical treatment of CCPA in medically refractory disease. This case is unique because our patient is relatively young and otherwise healthy, with no associated chronic lung disease.
慢性空腔性肺曲霉菌病:一名24岁煤矿工人慢性咳嗽、胸膜炎和咯血的罕见原因
当堆肥、灰尘和植物材料中发现的孢子被吸入时,肺曲霉菌感染是由无处不在的真菌霉菌引起的。该疾病的表现表现为宿主和病原体相互作用之间的微妙平衡,使曲霉菌感染在免疫功能受损的个体中更常见。慢性空洞性肺曲霉菌病(CCPA)是一种与慢性或既往肺部疾病史相关的肺曲霉病亚型。在这里,我们介绍了一例非免疫功能低下的24岁男性,他有间歇性哮喘病史,有慢性肺部症状,并在影像学上发现肺部肿块。我们描述了CCPA在医学难治性疾病中的诊断挑战和外科治疗。这种情况是独特的,因为我们的患者相对年轻,其他方面都很健康,没有相关的慢性肺病。
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