Study of Clinical Profiles, Risk Factors and Coronary Angiographic Patterns in Female Patients Presenting with Anginal Chest Pain in a Tertiary Care Centre of Nepal

IF 0.1 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
S. Adhikari, R. Gajurel, C. Poudel, H. Shrestha, S. Thapa, S. Devkota, B. Manandhar, R. Khanal, S. Shakya, V. Yadav, Manju Sharma, Ravi Sahi, Jeevan Thapa
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引用次数: 1

Abstract

Background and Aims: Coronary artery disease is one of the important causes of deaths in females in many countries. Females with chest pain are more likely to be treated in a different way as compared to males at the time of presentation. Worldwide, there has been a considerable rise in the number of females who are undergoing coronary angiography recently. Methods: This study was a single-centre, prospective, observational study conducted in the department of cardiology, MCVTC, Tribhuvan University, Nepal. The study period was from 5th  July 2020 to  4th July 2021.155 female patients with anginal chest pain were enrolled. Data were collected after thorough history taking, physical examination, laboratory investigations, and coronary angiography. They were further divided into three age groups:<50 years,50-65 years and >65 years. Subsequently statistical analysis was done using latest version of SPSS. Results: The mean age of the patients was 59.64 years (SD=11.428). There were 119 (76.77%) postmenopausal patients. The most prevalent risk factor of IHD  was HTN (43.87% ). Obesity/overweight was most common (58.62%) in those with age <50 years. DM was most common (26.32%) in age group 50-65 years. HTN was the most prevalent (52.63%) in age group 50-65 years. The maximum proportion of dyslipidemic patients (34.21%) were found in age group 50-65 years. 52.25% patients presented with acute coronary syndrome. 33.55% patients had normal coronary arteries. 11.61% patients had nonobstructive coronary artery disease. Obstructive coronary artery disease was found in 51.61% patients. IN patients with obstructive CAD, LAD was the most commonly involved vessel followed by RCA . Conclusion: Findings from our study shows higher prevalence of risk factors for IHD in Nepalese females. This study also demonstrates that as females get older and become postmenopausal, the number of risk factors for CAD increases. Understanding the risk factors for CAD and angiographic patterns in females could be helpful in implementing optimal treatment strategies in females with angina.
尼泊尔一家三级医疗中心女性心绞痛患者的临床特征、危险因素和冠状动脉造影模式研究
背景和目的:冠状动脉疾病是许多国家女性死亡的重要原因之一。与男性相比,患有胸痛的女性在出现胸痛时更有可能以不同的方式接受治疗。在全球范围内,最近接受冠状动脉造影的女性人数有了相当大的增长。方法:本研究是一项在尼泊尔特里布万大学MCVTC心脏病学系进行的单中心前瞻性观察性研究。研究期间为2020年7月5日至2021年7月4日。共有55名女性心绞痛患者入选。在全面的病史采集、体格检查、实验室调查和冠状动脉造影后收集数据。他们被进一步分为三个年龄组:65岁。随后使用最新版本的SPSS进行统计分析。结果:患者平均年龄59.64岁(SD=11.428),绝经后患者119例(76.77%)。IHD最常见的危险因素是HTN(43.87%)。肥胖/超重在年龄<50岁的人群中最为常见(58.62%)。糖尿病在50-65岁年龄组最常见(26.32%)。HTN在50-65岁年龄组中最为普遍(52.63%)。血脂异常患者的比例最大(34.21%)发生在50-65岁的年龄组。52.25%的患者出现急性冠状动脉综合征。33.55%的患者冠状动脉正常。11.61%的患者有非阻塞性冠状动脉疾病。51.61%的患者患有阻塞性冠状动脉疾病。在梗阻性CAD患者中,LAD是最常见的受累血管,其次是RCA。结论:我们的研究结果表明,尼泊尔女性IHD的危险因素患病率较高。这项研究还表明,随着女性年龄的增长和绝经后,CAD的风险因素数量会增加。了解女性冠心病的危险因素和血管造影模式可能有助于实施女性心绞痛的最佳治疗策略。
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来源期刊
Nepalese Heart Journal
Nepalese Heart Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
50.00%
发文量
16
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