Helicobacter pylori infection and related factors among pregnant women at Debre Tabor General Hospital, Northwest Ethiopia, 2021: Anemia highly related with H. pylori

IF 2.7 Q2 OBSTETRICS & GYNECOLOGY

Womens Health Pub Date : 2022-01-01 DOI:10.1177/17455057221092266

H. Yisak, Debaka Belete, Yeserk Mahtsentu

{"title":"Helicobacter pylori infection and related factors among pregnant women at Debre Tabor General Hospital, Northwest Ethiopia, 2021: Anemia highly related with H. pylori","authors":"H. Yisak, Debaka Belete, Yeserk Mahtsentu","doi":"10.1177/17455057221092266","DOIUrl":null,"url":null,"abstract":"Introduction: Infection with Helicobacter pylori is one of the most frequent chronic bacterial illnesses in humans. Pregnant mothers are the populations most vulnerable to H. pylori infection. The objective of this study was to assess the prevalence of H. pylori infection and associated factors among pregnant mothers having antenatal care at Debre Tabor General Hospital, Debre Tabor, Ethiopia, 2021. Methods and materials: Institutional based cross-sectional study design was conducted on 290 pregnant women. The stool antigen test is used to detect the active presence of the H. pylori antigen in the feces. Bivariate and multivariable logistic regression analyses were carried out to assess potential factors responsible for H. pylori infection. Variables associated with the prevalence of H. pylori infection with (p-value < 0.05) were considered statistically significant. Results: The prevalence of H. pylori infection was 17.9%, with 95% (CI: 13.4%–22.3%). In all, 65.4% of H. pylori infection positive mothers had gastrointestinal problems and developed symptoms like abdominal cramp and diarrhea 1 (1.92%), loss of appetite 10 (19.23%), hiccups 9 (17.31%), abdominal pain which worsens when the stomach is empty 19 (36.54%), indigestion, and frequent heart burn 13 (25%) during the present pregnancy. Lesser frequency of handwashing practice AOR = 3.09, 95% CI (1.14–8.34), use of soap for handwashing AOR = 0.44, 95% CI (0.19–0.98), eating unwashed vegetables and fruits AOR = 2.279, 95% CI (1.03–5.04), and not being anemic AOR = 0.268, 95% CI (0.10– 0.71), were significantly associated with H. pylori infection. Conclusions: This study shows that the prevalence of H. pylori infection among pregnant women was low compared with that of the general population. Although in the lower prevalence, the level of anemia was strongly associated with the prevalence of H. pylori infection. This implies that H. pylori infection is a public health problem.","PeriodicalId":47398,"journal":{"name":"Womens Health","volume":" ","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Womens Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/17455057221092266","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 4

Abstract

Introduction: Infection with Helicobacter pylori is one of the most frequent chronic bacterial illnesses in humans. Pregnant mothers are the populations most vulnerable to H. pylori infection. The objective of this study was to assess the prevalence of H. pylori infection and associated factors among pregnant mothers having antenatal care at Debre Tabor General Hospital, Debre Tabor, Ethiopia, 2021. Methods and materials: Institutional based cross-sectional study design was conducted on 290 pregnant women. The stool antigen test is used to detect the active presence of the H. pylori antigen in the feces. Bivariate and multivariable logistic regression analyses were carried out to assess potential factors responsible for H. pylori infection. Variables associated with the prevalence of H. pylori infection with (p-value < 0.05) were considered statistically significant. Results: The prevalence of H. pylori infection was 17.9%, with 95% (CI: 13.4%–22.3%). In all, 65.4% of H. pylori infection positive mothers had gastrointestinal problems and developed symptoms like abdominal cramp and diarrhea 1 (1.92%), loss of appetite 10 (19.23%), hiccups 9 (17.31%), abdominal pain which worsens when the stomach is empty 19 (36.54%), indigestion, and frequent heart burn 13 (25%) during the present pregnancy. Lesser frequency of handwashing practice AOR = 3.09, 95% CI (1.14–8.34), use of soap for handwashing AOR = 0.44, 95% CI (0.19–0.98), eating unwashed vegetables and fruits AOR = 2.279, 95% CI (1.03–5.04), and not being anemic AOR = 0.268, 95% CI (0.10– 0.71), were significantly associated with H. pylori infection. Conclusions: This study shows that the prevalence of H. pylori infection among pregnant women was low compared with that of the general population. Although in the lower prevalence, the level of anemia was strongly associated with the prevalence of H. pylori infection. This implies that H. pylori infection is a public health problem.

查看原文本刊更多论文

埃塞俄比亚西北部Debre Tabor综合医院孕妇幽门螺杆菌感染及相关因素，2021：贫血与幽门螺杆菌高度相关

引言：幽门螺杆菌感染是人类最常见的慢性细菌性疾病之一。孕妇是最容易感染幽门螺杆菌的人群。本研究的目的是评估2021年在埃塞俄比亚Debre Tabor Debre Tabor-综合医院接受产前护理的孕妇中幽门螺杆菌感染的流行率和相关因素。方法和材料：对290名孕妇进行了基于机构的横断面研究设计。粪便抗原测试用于检测粪便中幽门螺杆菌抗原的活性存在。进行双变量和多变量逻辑回归分析，以评估幽门螺杆菌感染的潜在因素。与幽门螺杆菌感染流行率相关的变量（p值 < 0.05）被认为具有统计学意义。结果：幽门螺杆菌感染的患病率为17.9%，95%（CI:13.4%-22.3%）。总的来说，65.4%的幽门螺杆菌阳性母亲有胃肠道问题，并出现腹部痉挛和腹泻1（1.92%）、食欲不振10（19.23%）、打嗝9（17.31%）、空腹时腹痛恶化19（36.54%）、消化不良，在本次妊娠期间频繁的心脏烧伤13例（25%）。洗手次数较少AOR = 3.09，95%置信区间（1.14-8.34），使用肥皂洗手AOR = 0.44，95%置信区间（0.19–0.98），食用未清洗的蔬菜和水果AOR = 2.279，95%置信区间（1.03–5.04），无贫血AOR = 0.268，95%CI（0.10-0.71）与幽门螺杆菌感染显著相关。结论：本研究表明，与普通人群相比，孕妇幽门螺杆菌感染的患病率较低。尽管患病率较低，但贫血水平与幽门螺杆菌感染的患病率密切相关。这意味着幽门螺杆菌感染是一个公共卫生问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Womens Health OBSTETRICS & GYNECOLOGY-

CiteScore

2.80

自引率

4.20%

发文量

审稿时长

15 weeks

期刊介绍： For many diseases, women’s physiology and life-cycle hormonal changes demand important consideration when determining healthcare management options. Age- and gender-related factors can directly affect treatment outcomes, and differences between the clinical management of, say, an adolescent female and that in a pre- or postmenopausal patient may be either subtle or profound. At the same time, there are certain conditions that are far more prevalent in women than men, and these may require special attention. Furthermore, in an increasingly aged population in which women demonstrate a greater life-expectancy.