Experimental study on acoustic-induced microbubbles fusion

IF 2.4 4区工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

Journal of Micromechanics and Microengineering Pub Date : 2023-08-09 DOI:10.1088/1361-6439/acee87

Shaobo Jin, N. Cao, G. Ye, P. Wang, Shizhang Dong, Zenghao Liu

引用次数: 0

Abstract

Droplets/microbubbles fusion technology is a key technology for many biochemical medical applications. Here, an acoustic-controlled approach to drive microbubble fusion based on focused surface acoustic wave (FSAW) is presented. When passing through the arc-shaped channel, adjacent microbubbles will decelerate, contact, and fuse induced by the FSAWs. Due to the cooperation of the FSAW and the arc-shaped flow channel structure, the microbubbles are more easily captured and fused with the adjacent microbubbles. The effects of input voltage and pressure input parameters on the microbubble fusion are studied. Relying on electrical input parameters, microbubble fusion can be effectively achieved, providing a new idea for precise gas fuse control. The regulation of the microbubbles fusion by FSAW is revealed, showing potential in the applications of the precise control of gases on a microfluidic chip.

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声学诱导微气泡融合的实验研究

液滴/微气泡融合技术是许多生化医学应用的关键技术。本文提出了一种基于聚焦表面声波（FSAW）的声学控制方法来驱动微气泡融合。当通过弧形通道时，相邻的微气泡将减速、接触并融合FSAW诱导的微气泡。由于FSAW和弧形流道结构的配合，微气泡更容易被捕获并与相邻的微气泡融合。研究了输入电压和压力输入参数对微气泡融合的影响。依靠电输入参数，可以有效地实现微气泡融合，为精确控制气体引信提供了新的思路。揭示了FSAW对微气泡融合的调控，显示出在微流控芯片上精确控制气体应用的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Micromechanics and Microengineering 工程技术-材料科学：综合

CiteScore

4.50

自引率

4.30%

发文量

136

审稿时长

2.8 months

期刊介绍： Journal of Micromechanics and Microengineering (JMM) primarily covers experimental work, however relevant modelling papers are considered where supported by experimental data. The journal is focussed on all aspects of: -nano- and micro- mechanical systems -nano- and micro- electomechanical systems -nano- and micro- electrical and mechatronic systems -nano- and micro- engineering -nano- and micro- scale science Please note that we do not publish materials papers with no obvious application or link to nano- or micro-engineering. Below are some examples of the topics that are included within the scope of the journal: -MEMS and NEMS: Including sensors, optical MEMS/NEMS, RF MEMS/NEMS, etc. -Fabrication techniques and manufacturing: Including micromachining, etching, lithography, deposition, patterning, self-assembly, 3d printing, inkjet printing. -Packaging and Integration technologies. -Materials, testing, and reliability. -Micro- and nano-fluidics: Including optofluidics, acoustofluidics, droplets, microreactors, organ-on-a-chip. -Lab-on-a-chip and micro- and nano-total analysis systems. -Biomedical systems and devices: Including bio MEMS, biosensors, assays, organ-on-a-chip, drug delivery, cells, biointerfaces. -Energy and power: Including power MEMS/NEMS, energy harvesters, actuators, microbatteries. -Electronics: Including flexible electronics, wearable electronics, interface electronics. -Optical systems. -Robotics.